不同时机宫体注射欣母沛预产后出血的临床效果观察  

Clinical Effect of Different Time Uterine Injection of Hemabate on Prevention of Postpartum Hemorrhage with Uterine Atony during Caesarean Section

作　　者：张桂馨 ZHANG Guixin(Dandong Ceneral Hospital,Dandong 118002,China)

机构地区：[1]丹东市中心医院,辽宁丹东118002

出　　处：《中国医药指南》2021年第23期49-50,共2页Guide of China Medicine

摘　　要：目的探讨不同时机宫体注射欣母沛预产后出血的临床效果。方法以72例在我院行剖宫产术的孕产妇为观察对象,住院时间为2017年8月至2018年12月,所有产妇在胎儿娩出后立即注射缩宫素,采用随机数字表法将患者进行平均分组,将其中36例在宫缩乏力时注射欣母沛的产妇纳入对照组,另外36例注射宫缩素后立即注射欣母沛的产妇纳入观察组,对比两组患者术中、术后2 h及术后24 h出血量,对比两组产后出血发生率,记录两组不良反应率。结果治疗后,观察组产妇术中、术后2 h及术后24 h出血量明显少于对照组(P<0.05);不同时机给药后,观察组产妇不良反应率为8.33%,与对照组11.11%不良反应率比较,无明显差异(P>0.05);不同时机给药后,观察组产妇产后出血发生率为5.56%,对照组为33.33%,观察组明显少于对照组(P<0.05)。结论对行剖宫产的产妇在其注射缩宫素后,立即注射欣母沛能减少产妇出血量,减少产后出血发生率,不良反应率未见明显增加,值得临床医学进一步研究与使用。Objective To investigate the clinical effects of injection of hemabate into the uterine body at different times to pretreat postpartum hemorrhage.Method Taking 72 pregnant women undergoing cesarean section in our hospital as the observation object,the hospitalization time was from August 2017 to December 2018.All the pregnant women were injected with oxytocin immediately after the fetus was delivered,and the patients were treated by random number table method.The average grouping was carried out.Among them,36 parturients who were injected with hemabate during uterine weakness were included in the control group,and the other 36 cases who were injected with hemabate immediately after injection of oxytocin were included in the observation group.The intraoperative and operative procedures of the two groups were compared.After 2 hours and 24 hours postoperative bleeding,the incidence of postpartum hemorrhage between the two groups was compared,and the adverse reaction rate of the two groups was recorded.Results After treatment,the blood loss during operation,2 hours after operation,and 24 hours after operation in the observation group was significantly less than that in the control group(P<0.05);after different timing of administration,the adverse reaction rate of the observation group was 8.33%,which was compared with that in the control group(11.11%),there was no significant difference in the adverse reaction rate(P>0.05);after administration of different timings,the incidence of postpartum hemorrhage in the observation group was 5.56%,and that of the control group was 33.33%,the observation group was significantly less than the control group(P<0.05).Conclusion For the parturients undergoing cesarean section,after the injection of oxytocin,the immediate injection of hemabate can reduce the amount of maternal bleeding and reduce the incidence of postpartum hemorrhage,the adverse reaction rate has not increased significantly.It is worthy of further research and use in clinical medicine.

关 键 词：宫缩乏力 产后出血 欣母沛 宫体注射 剖宫产术 

分 类 号：R714.461[医药卫生—妇产科学]