自拟消荨汤联合枸地氯雷他定片治疗慢性荨麻疹的临床效果  

Clinical effect of self-made Xiaoxun decoction combined with desloratadine citrate disodium tablets in the treatment of chronic urticaria

作　　者：赵玢 刘乐 ZHAO Bin;LIU Le(Dermatology Department,Xi'an International Medical Center Hospital,Xi'an 710100;DermatologyDepartment,Shaanxi Institute of Dermatology and Venereology,Xi'an 710006,China)

机构地区：[1]西安国际医学中心医院皮肤科,陕西西安710100 [2]陕西省皮肤性病防治所皮肤科,陕西西安710006

出　　处：《临床医学研究与实践》2021年第24期148-150,共3页Clinical Research and Practice

摘　　要：目的探究自拟消荨汤联合枸地氯雷他定片治疗慢性荨麻疹(CU)的临床效果。方法将我院2018年2月至2020年1月收治的116例CU患者随机分为对照组和观察组,各58例。对照组予以枸地氯雷他定片治疗,观察组在此基础上联合自拟消荨汤治疗。比较两组的治疗效果。结果观察组的治疗总有效率显著高于对照组(P<0.05);治疗3周后,两组的UAS、VAS、DLQI评分均较治疗前显著降低,且观察组显著低于对照组(P<0.05);治疗3周后,两组的血清IL-4、IL-13及IgE水平均较治疗前显著降低,且观察组显著低于对照组(P<0.05);停药4周后,观察组的复发率显著低于对照组(P<0.05)。结论自拟消荨汤联合枸地氯雷他定片治疗CU,有利于改善患者的临床症状,提高生活质量,降低复发率,具有较好的实用性,可在临床上推广应用。Objective To explore the clinical effect of self-made Xiaoxun decoction combined with desloratadine citrate disodium tablets in the treatment of chronic urticaria(CU).Methods A total of 116 CU patients admitted in our hospital from February 2018 to January 2020 were randomly divided into control group and observation group,with 58 cases in each group.The control group was treated with desloratadine citrate disodium tablets,and the observation group was treated with self-made Xiaoxun decoction on this basis.The therapeutic effects of the two groups were compared.Results The total effective rate of treatment in the observation group was significantly higher than that in the control group(P<0.05).After 3 weeks of treatment,the UAS,VAS and DLQI scores in the two groups were significantly lower than those before treatment,and those in the observation group were significantly lower than the control group(P<0.05).After 3 weeks of treatment,the levels of serum IL-4,IL-13 and IgE in the two groups were significantly lower than those before treatment,and those in the observation group were significantly lower than the control group(P<0.05).After 4 weeks of drug withdrawal,the recurrence rate in the observation group was significantly lower than that in the control group(P<0.05).Conclusion The self-made Xiaoxun decoction combined with desloratadine citrate disodium tablets in the treatment of CU is helpful to improve the clinical symptoms and the quality of life,and reduce the recurrence rate.It has good practicability and can be popularized and applied in clinic.

关 键 词：自拟消荨汤 枸地氯雷他定片 慢性荨麻疹 

分 类 号：R98[医药卫生—药品]