化妆品中新补骨脂异黄酮、补骨脂二氢黄酮、补骨脂素和异补骨脂素含量的测量不确定度评定  

Evaluation of Measurement Uncertainty in the Determination of Neobavaisoflavone,Bavachin,Psoralen and Lsopsoralen in Cosmetics

作　　者：范菲 黄炯力 安庆 崔颖 朱清 FAN Fei;HUANG Jiong-li;AN Qing;CUI Ying;ZHU Qing(Xi'an Institute for Food and Drug Control,Xi'an,Shaanxi 710054,China;Xi'an Institute of Measurement and Testing Technology,Xi'an,Shaanxi 710068,China)

机构地区：[1]西安市食品药品检验所,陕西西安710054 [2]西安计量技术研究院,陕西西安710068

出　　处：《计量学报》2021年第8期1094-1100,共7页Acta Metrologica Sinica

摘　　要：用高效液相色谱法测定化妆品中新补骨脂异黄酮、补骨脂二氢黄酮、补骨脂素和异补骨脂素含量,建立数学模型,分析检测过程中不确定度的来源,给出量化结果,得到标准不确定度和扩展不确定度。结果表明,当取95%置信概率,包含因子k为2,被测样品中新补骨脂异黄酮、补骨脂二氢黄酮、补骨脂素和异补骨脂素的含量分别为42.61μg/g、44.04μg/g、42.94μg/g和41.90μg/g时,相应的扩展不确定度为1.65μg/g、1.82μg/g、1.66μg/g和1.61μg/g。分析了测量不确定度的主要来源,并提出了改进建议。Uncertainties from the determination procedure of neobavaisoflavone,bavachin,psoralen and lsopsoralen in cosmetics by high performance liquid chromatography(HPLC)were assessed.The mathematical model was established,and each source and uncertainty component were analyzed.The standard uncertainty and expanded uncertainty were reported at last.The results showed that the expanded uncertainties were 1.65μg/g,1.82μg/g,1.66μg/g and 1.61μg/g(95%confidence level,k=2),when the content of neobavaisoflavone,bavachin,psoralen and lsopsoralen in cosmetics were 42.61μg/g,44.04μg/g,42.94μg/g and 41.90μg/g.The main sources for the uncertainty were discussed,and suggestions for improvement were also introduced.

关 键 词：计量学 化妆品组分检测 新补骨脂异黄酮 补骨脂二氢黄酮 补骨脂素 异补骨脂素 不确定度 

分 类 号：TB99[一般工业技术—计量学]