有氧训练对代谢综合征患者动脉僵硬的影响  

Effect of aerobic training on arterial stiffness in patients with metabolic syndrome

作　　者：刘凯[1] 吴晓华[1] 卢少泉[1] 高照[1] 董霄 郑茵[1] 吕静美[1] Liu Kai;Wu Xiaohua;Lu Shaoquan;Gao Zhao;Dong Xiao;Zheng Yin;Lyu Jingmei(Health Care Center,the People′s Hospital of Hainan,Haikou 570311,China)

机构地区：[1]海南省人民医院医疗保健中心,海口570311

出　　处：《中国临床保健杂志》2021年第4期483-488,共6页Chinese Journal of Clinical Healthcare

基　　金：海南省医药卫生科研项目(1801320241A2007)。

摘　　要：目的评估心率(HR)定向有氧运动训练对代谢综合征患者动脉僵硬的影响。方法连续纳入126例代谢综合征受试者。在8周(84例患者)的监督训练前后分别采集人体测量参数、血压(BP)、实验室指标、动脉壁功能和结构参数,年龄和性别匹配的42例患者作为对照组。结果在研究组中,HR定向训练与降低主动脉脉搏波速度[治疗前:(8.35±1.39)m/s,治疗后:(7.83±0.94)m/s,P=0.014]、心率(P<0.001)、收缩压(P<0.001)和舒张压(P=0.002)、腰围(P=0.002)、总胆固醇[治疗前:(6.47±1.41)mmol/L,治疗后:(5.97±1.35)mmol/L,P<0.001]和低密度脂蛋白胆固醇[治疗前:(5.60±1.14)mmol/L,治疗后:(5.39±1.18)mmol/L],P=0.041有关,有氧运动能力增加(P<0.001)。对照组动脉硬度参数差异无统计学意义。多变量分析显示动脉僵硬度的降低与血压有关。结论在代谢综合征的受试者中,心率靶向运动训练与血压依赖性的主动脉僵硬度降低及代谢和健康参数的改善相关。Objective To evaluate the effect of heart rate(HR)orientated aerobic exercise training on arterial stiffness in patients with metabolic syndrome.Methods One hundred and twenty six subjects with metabolic syndrome were randomly selected.The anthropometric parameters,blood pressure(BP),laboratory parameters,arterial wall function and structural parameters were collected before and after 8 weeks of supervisory training.42 patients matched with age and sex were taken as control group.Results In the study group,HR directional training reduced aortic pulse wave velocity[(8.35±1.39)m/s vs.(7.83±0.94)m/s,P=0.014],heart rate(P<0.001),systolic pressure(P<0.001),diastolic pressure(P=0.002),waist circumference(P=0.002),total cholesterol[(6.47±1.41)mmol/L vs.(5.97±1.35)mmol/L,P<0.001],and low density lipoprotein cholesterol(LDL-C).Alcohol[(5.60±1.14)mmol/L vs.(5.39±1.18)mmol/L,P=0.041]was related,and aerobic exercise ability increased(P<0.001).There was no significant difference in arterial stiffness parameters between the control group and the control group.Multivariate analysis showed that the decrease of arterial stiffness was related to blood pressure.Conclusion Heart rate targeting exercise training is associated with reduced blood pressure-dependent aortic stiffness and improve metabolic and health parameters in patients with metabolic syndrome.

关 键 词：代谢综合征 动脉硬化程度 身体锻炼 心率 

分 类 号：R54[医药卫生—心血管疾病]