用运动控制器来终止心律失常  

Terminating Arrhythmia by Using Motion Controller

作　　者：白婧 黄志精 唐国宁[1] BAI Jing;HUANG Zhijing;TANG Guoning(College of Physical science and Technology,Guangxi Normal University,Guilin y Guangxi 541004,China)

机构地区：[1]广西师范大学物理科学与技术学院,广西桂林541004

出　　处：《计算物理》2021年第3期352-360,共9页Chinese Journal of Computational Physics

基　　金：国家自然科学基金(11565005、11947413)资助项目。

摘　　要：采用Luo-Rudy相Ⅰ心脏模型对通过局部电击使细胞复极化来消除心脏中的螺旋波和时空混沌进行数值模拟。提出利用控制器局部电击螺旋波波头周围的心肌细胞来抑制螺旋波的旋转,使螺旋波漂移出边界,进而控制螺旋波和时空混沌。数值模拟表明:适当选择控制的格点数和膜电位控制阈值,螺旋波和时空混沌都可以被抑制。最少的控制格点数为9个,最短的单螺旋波控制时间小于150 ms,最短的时空混沌控制时间小于500 ms。A control method suppressing spiral wave and spatiotemporal chaos by using local electric shock produced by moving controller is proposed.The local electric shock is to myocardial cells around spiral wave tip to suppress the rotation of spiral wave tip,causing spiral wave tip to move out of the boundary.We studied numerically with Luo-Rudy phase I heart model.It shows that with appropriate number of grid points controlled by local electrical shock and the control thresholds of membrane potential,both spiral wave and spatiotemporal chaos can be suppressed.The minimum number of controlled grid points is 9.The shortest control times of spiral wave and spatiotemporal chaos are less than 150 ms and 500 ms,respectively.

关 键 词：心律失常 螺旋波 时空混沌 膜电位控制阈值 

分 类 号：O415.5[理学—理论物理]