甘肃金昌市2012-2018年5岁以下儿童病毒性腹泻流行及病原特征  

Epidemic and pathogenic characteristics of viral diarrhea in children under 5 years of age in JinchangCity,GansuProvince from 2012 to 2018

作　　者：姚淑英[1] 张远斌 聂永红[1] Yao Shuying;ZhangYuanbin;NieYonghong(Department of Laboratory,Center for Disease Control and Prevention of JinchangCity,GansuJinchang 737100)

机构地区：[1]金昌市疾病预防控制中心检验科,甘肃金昌737100

出　　处：《中国社区医师》2021年第24期188-189,共2页Chinese Community Doctors

基　　金：“十二五”国家科技重大专项“甘肃及周边省(区)传染病病原谱流行规律研究”(2012ZX10004-208);2012-2018年金昌市感染性腹泻病原谱调查研究与分析,编号:2019BDJSVX。

摘　　要：目的:分析金昌市病毒性腹泻的流行特征及病原学构成。方法:对金昌市2012-2018年4家医院采集的病毒性腹泻病例样本进行病毒核酸检测,统计分析实验室检测结果(描述流行病学方法)。结果:共采集腹泻病例标本2116份,病毒核酸检测阳性率依次为轮状病毒19.90%、杯状病毒12.00%、星状病毒3.97%、腺病毒3.73%;轮状病毒具有明显的季节高峰,其基因型主要为G3、G9、P8,诺如病毒感染率12.00%,星状病毒、腺病毒维持在较低水平。结论:儿童腹泻存在较高的病毒感染率,以A组轮状病毒和诺如Ⅱ型病毒为主要病毒,同时存在混合感染模式。Objective:To analyze the epidemiological characteristics and pathogenic composition of viral diarrhea in JinchangCity.Methods:Viral nucleic acid tests were performed on samples of viral diarrhea cases collected from four hospitals in Jinchang City from 2012 to 2018,and laboratory test results were statistically analyzed(describe epidemiological methods).Results:A total of 2116 specimens of diarrhea cases were collected,and the positive rate of viral nucleic acid detection was 19.90%for rotavirus,12.00% for calicivirus,3.97% for astrovirus,and 3.73% for adenovirus.Rotavirus has an obvious seasonal peak.The genotypes were mainly G3,G9,P8,the infection rate of norovirus was 12.00%,and the astrovirus and adenovirus were maintained at a low level.Conclusion:Children's diarrhea has a high viral infection rate.The group A rotavirus and norovirus typeⅡare the main viruses,and there is a mixed infection mode at the same time.

关 键 词：病毒性腹泻 病原谱 基因型别 流行学 

分 类 号：R725.1[医药卫生—儿科] R181.3[医药卫生—临床医学]