Detection of Schistosoma Antibodies and exploration of associated factors among local residents around Inlay Lake,Southern Shan State,Myanmar  

作　　者：Htin Zaw Soe Cho Cho Oo Tin Ohn Myat Nay Soe Maung 

机构地区：[1]University of Community Health,Magway,Myanmar [2]University of Medicine(Mandalay),Mandalay,Myanmar [3]University of Medicine(I),Yangon,Myanmar [4]University of Public Health,Yangon,Myanmar

出　　处：《Infectious Diseases of Poverty》2017年第1期19-24,共6页贫困所致传染病（英文）

基　　金：The research project was funded by World Health Organization.Project name:SYSSER 2012-2013;Project number:SEMMR 1207308;OSER number:10.009.SEO1.MMRO3;Top task number:24.3.

摘　　要：Background:Schistosomiasis is a chronic parasitic disease caused by blood flukes(trematode worms)of the genus Schistosoma.Its transmission has been reported in 78 countries affecting at least 258 million people world-wide.It was documented that S.japonicum species was prevalent in Shan State,Myanmar,but the serological study was not conducted yet.General objective of the present study was to detect schistosoma antibodies and explore associated factors among local residents living around Inlay Lake,Nyaung Shwe Township,and Southern Shan State,Myanmar.Methods:An exploratory and cross-sectional analytic study was conducted among local residents(n=315)in selected rural health center(RHC)areas from December 2012 through June 2013.The participants were interviewed with pretested semi-structured questionnaires and their blood samples(serum)were tested using Schistosomiasis Serology Microwell ELISA test kits(sensitivity 100%and specificity 85%)which detected IgG antibodies but could not distinguish between a new and past infection.Data collected were analysed by SPSS software 16.0 and associations of variables were determined by Chi-squared test with a significant level set at 0.05.Results:Schistosoma seroprevalence(IgG)in study area was found to be 23.8%(95%CI:18.8-28.8%).The present study is the first and foremost study producing serological evidence of schistosoma infection-one of the neglected tropical diseases-in local people of Myanmar.The factors significantly associated with seropositivity were being male[OR=2.6(95%CI:1.5-4.49),P<0.001],residence[OR=3.41(95%CI:1.6-7.3),P<0.05 for Khaung Daing vs.Min Chaung]and education levels[OR=4.5(95%CI:1.18-17.16),P<0.05 for illiterate/3Rs level vs.high/graduate and OR=3.16(95%CI:1.26-7.93),P<0.05 for primary/middle level vs.high/graduate]all factors classically associated with risk of schistosoma infection.None of the behavioural factors tested were significantly associated with seropositivity.Conclusion:Schistosoma infection serologically detected was most probably present

关 键 词：SCHISTOSOMIASIS Associated factors Inlay Lake Myanmar SEROPREVALENCE Elisa 

分 类 号：R53[医药卫生—内科学]