Plague risk in vulnerable community:assessment of Xenopsylla cheopis susceptibility to insecticides in Malagasy prisons  

作　　者：Adelaide Miarinjara Jean Vergain Jean Marcel Kavaruganda Minoarisoa Rajerison Sebastien Boyer 

机构地区：[1]United’Entomologie Medicale,Institut Pasteur de Madagascar,Ambatofotsikely,101 Antananarivo,PO box 1274,Madagascar [2]Ecole Doctorale Sciences de la Vie et de l’Environnement,Universited’Antananarivo,Antananarivo,Madagascar [3]Delegation Regionale pour l’Ocean Indien,ComiteInternational de la Croix-Rouge(CICR),112,Rue Rainandriamampandry,Lot II B 16-Faravohitra,101 Antananarivo,Madagascar [4]UnitePeste,Institut Pasteur de Madagascar,Ambatofotsikely,101 Antananarivo,PO box 1274,Madagascar.

出　　处：《Infectious Diseases of Poverty》2017年第1期1255-1261,共7页贫困所致传染病（英文）

基　　金：The fleas tested here were collected during rodent control campaign funded by the Swiss Embassy-Antananarivo(Ref#771.22.00-1-MAE/RML);Laboratory works were funded by Institut Pasteur de Madagascar.

摘　　要：Background:Prisons in Madagascar are at high risk of plague outbreak.Occurrence of plague epidemic in prisons can cause significant episode of urban plague through the movement of potentially infected humans,rodents and fleas.Rodent and flea controls are essential in plague prevention,by reducing human contact with plague reservoirs and vectors.Insecticide treatment is the key step available for the control of rat fleas which transmit the disease from infected rodents to human.The implementation of an adapted flea control strategy should rely on the insecticide susceptibility status of the targeted population.For the purpose of plague prevention campaign in prisons,we conducted insecticide resistance survey on Xenopsylla cheopis,the rat flea.Methods:Fleas were collected on rats caught in six prisons of Madagascar.They were exposed to insecticide treated filter papers and mortality was recorded following World Health Organization protocol.Results:The fleas collected in the prisons had different resistance patterns,while a high level of resistance to insecticides tested was described in the Antanimora prison,located in the heart of Antananarivo,the capital of Madagascar.Conclusions:This finding is alarming in the context of public health,knowing that the effectiveness of flea control could be jeopardized by insecticide resistance.In order to establish more accurate rat fleas control in prisons,the main recommendations are based on continuous monitoring insecticide susceptibility of flea,insecticide rotation,and the development of a new method for flea control.

关 键 词：PLAGUE PRISON FLEA INSECTICIDE Madagascar 

分 类 号：D62[政治法律—政治学]