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作 者:Jiaxin Tang Huaimin Zhu Li Cai Tingting Tang Jian Tang Yuehua Sun Ming Liu Kerong Dai Zhiguang Qiao Chao Yu
机构地区:[1]Shanghai Key Laboratory of Orthopaedic Implants,Department of Orthopaedic Surgery,Shanghai Ninth People’s Hospital,Shanghai Jiao Tong University School of Medicine,Shanghai 200011,China [2]Department of Microbiology and Parasitology,Second Military Medical University,Shanghai 200433,China [3]Shanghai Municipal Center for Disease Control&Prevention,Shanghai 200336,China [4]Medical 3D Printing Innovation Research Center,Shanghai Jiao Tong University School of Medicine,Shanghai 200125,China [5]Engineering Research Center of Digital Medicine and Clinical Translation,Ministry of Education,Shanghai 200030,China
出 处:《Infectious Diseases of Poverty》2018年第1期335-343,共9页贫困所致传染病(英文)
基 金:This work was supported by grants from National Natural Science Foundation of China(31271015);Key Basic Research Project of Science and Technology of Shanghai(13JC1403900).
摘 要:Background:Acinetobacter baumannii is ubiquitous,facultative intracellular,and opportunistic bacterial pathogen.Its unique abilities allow it to survive in a diverse range of environments,including health care settings,leading to nosocomial infections.And its exceptional ability to develop resistance to multiple antibiotics leaves few drug options for treatment.It has been recognized as a leading cause of nosocomial pneumonia and bacteremia over the world.Case presentation:In this case,a 73-year-old woman presented with a Neer Group VI proximal humeral fracture.Six hours after a successfully performed hemiarthroplasty,she developed continuous fever.Clinical examination revealed that the vitals were regular.Laboratory and radiographic examinations revealed only elevated procalcitonin levels.Blood culture revealed no bacterial or fungal growth.Cooling treatment and empirical broad-spectrum antibiotic therapy showed no apparent effect.Conclusions:We report a postoperative infection caused by Acinetobacter baumannii.The infectious pathogen was identified via molecular DNA sequencing and was initially misidentified as a free-living amoeba species upon microscopic examinations.The patient was mistreated with antiamebic combination therapy.Her symptoms persisted for over 4 months and were eventually followed by her death.
关 键 词:Acinetobacter baumannii Free-living amoebae HEMIARTHROPLASTY Case report
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