Prevalence of chronic infections and susceptibility to measles and varicellazoster virus in Latin American immigrants  

作　　者：Yves Jackson Lilian Santos Isabelle Arm-Vernez Anne Mauris Hans Wolff François Chappuis Laurent Getaz 

机构地区：[1]Division of Primary Care Medicine,Geneva University Hospitals and Faculty of Medicine,University of Geneva,Rue Gabrielle Perret Gentil 6,Geneva 1211,Switzerland [2]Institute of Global Health,University of Geneva,Geneva,Switzerland [3]Division of Tropical and Humanitarian Medicine,Geneva University Hospitals and Faculty of Medicine,University of Geneva,Geneva,Switzerland [4]Department of Genetics and Laboratory Medicine,Geneva University Hospitals and Faculty of Medicine,University of Geneva,Geneva,Switzerland [5]Division of Correctional Medicine and Psychiatry,Geneva University Hospitals and Faculty of Medicine,University of Geneva,Geneva,Switzerland

出　　处：《Infectious Diseases of Poverty》2016年第1期340-345,共6页贫困所致传染病（英文）

摘　　要：Background:Large numbers of Latin American immigrants recently arrived in Western Europe.Curative and preventive programmes need to take account of their risk of suffering and transmitting imported chronic infections and of their susceptibility to cosmopolitan infections.We aimed to assess the prevalence and co-occurrence of imported chronic infections among Latin American immigrants,and their susceptibility to highly prevalent cosmopolitan infections.Methods:Adult participants were recruited in the community and in a primary health centre in Geneva in 2008.Serological tests were performed on stored sera for HIV,HBV,syphilis,Strongyloides stercoralis,Trypanosoma cruzi,varicella and measles.We considered only chronic active infections in the analysis.Results and discussion:The 1012 participants,aged 37.2(SD 11.3)years,were mostly female(82.5%)and Bolivians(48%).Overall,209(20.7%)had at least one and 27(2.7%)two or more chronic infections.T.cruzi(12.8%)and S.stercoralis(8.4%)were the most prevalent chronic active infections compared to syphilis(0.4%),HBV(0.4%)and HIV(1.4%).Concomitant infections affected 28.2 and 18.5%of T.cruzi and S.stercoralis infected cases.Bolivian origin(aOR:13.6;95%CI:3.2–57.9)was associated with risk of multiple infections.Susceptibilities for VZV and measles were 0.7 and 1.4%,respectively.Latin American immigrants are at risk of complications and possible reactivation of chronic parasitic infections but have overall low risks of chronic viral and syphilitic active infections.Conclusions:Systematic screening for chronic active parasitic infections is therefore necessary especially among Bolivians.The high protection rate against measles and VZV doesn’t require specific preventive interventions.

关 键 词：IMMIGRANTS Europe Chronic infection CO-INFECTION Trypanosma cruzi Strongyloides stercoralis HIV 

分 类 号：R51[医药卫生—内科学]