Factors associated with needle sharing among people who inject drugs in Yunnan, China: a combined network and regression analysis  

作　　者：Xin Chen Lin Zhu Yan-Heng Zhou Feng-Liang Liu Hong Li Zhi-Hong Yao Lin Duo Wei Pang Mei Ye Yong-Tang Zheng 

机构地区：[1]Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and Yunnan Province,Kunming Institute of Zoology,Chinese Academy of Sciences,Kunming,Yunnan 650223,China [2]Yunnan Center for Disease Control and Prevention,Kunming,Yunnan 650022,China [3]The Second People’s Hospital of Yunnan Province,Kunming,Yunnan 650021,China [4]Kunming College of Life Science,University of Chinese Academy of Sciences,Kunming,Yunnan 650204,China [5]College of Life Sciences,Yan’an University,Yan’an,Shaanxi 716000,China

出　　处：《Infectious Diseases of Poverty》2016年第1期660-669,共10页贫困所致传染病（英文）

基　　金：supported in part by grants from the National Natural Science Foundation of China(81271892,U1302224,U1202228);the Key Scientific and Technological Program of China(2012ZX10001-006,2012ZX10001-007)。

摘　　要：Background:Network analyses have been widely utilized to evaluate large datasets,but have not yet been used to explore factors associated with risk behaviours.In combination with traditional regression analysis,network analyses may provide useful information and highlight key factors for reducing needle sharing behaviours among people who inject drugs(PWID).Methods:Sociodemographic data,and information on injection behaviour and sexual practices were collected from a cross-sectional survey that was conducted with PWID in five prefectures of Yunnan province,China.A combination of logistic regression and correlation network analyses were used to explore key factors for reducing needle-sharing behaviours among PWID.Results:In a total of 1049 PWID,37.5%had a history of needle or syringe sharing.The logistic analysis showed that Zhaotong,Qujing,Dehong,or Lincang residents,diazepam use,longer injection duration,needle reuse,and infection with HIV,viral hepatitis,tuberculosis and/or malaria were independently associated with needle sharing.The correlation network analyses showed that,compared to PWID who had never shared needles,PWID who did share needles would achieve harm reduction goals faster and more permanently.HIV serostatus and marital status were found to be closely associated with other risk factors.By combining regression analyses with network analyses,it was shown that PWID who are HIV seropositive will be an ideal target group for harm reduction programs.Conclusion:Needle-sharing behaviours are common among PWID in Yunnan,and harm reduction programs may help PWID who are HIV seropositive reduce risk behaviours and prevent blood borne diseases.

关 键 词：People who inject drugs Needle sharing Risk behaviours Network analysis Regression analysis China 

分 类 号：F42[经济管理—产业经济]