咳嗽变异性哮喘发病机制及中西药疗效的研究进展  

Research Progress of Pathogenesis of Cough Variant Asthma and Therapeutic Effect of Traditional Chinese Medicine and Western Medicine

作　　者：袁阳[1,2] 袁芳 郑权[3] 郭华[3] 李枝[3] 何成诗 YUAN Yang;YUAN Fang;ZHENG Quan;GUO Hua;LI Zhi;HE Chengshi(Department of Critical Care Medicine,Suining First People's Hospital,Suining 629000,China;Department of Respiratory Medicine,Affiliated Hospital of Chengdu University of Traditional Chinese Medicine,Chengdu 610075,China;Department of Respiratory Medicine,Suining First People's Hospital,Suining 629000,China)

机构地区：[1]四川省遂宁市第一人民医院重症医学科,629000 [2]成都中医药大学附属医院呼吸内科,四川省成都市610075 [3]四川省遂宁市第一人民医院呼吸内科,629000

出　　处：《实用心脑肺血管病杂志》2021年第8期135-140,共6页Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease

基　　金：四川省科技计划项目(2017SZ0164,2016JY0008)。

摘　　要：咳嗽变异性哮喘(CVA)是一种以慢性持续性咳嗽为主要临床表现的哮喘,其气道炎症机制复杂,病理生理机制尚未完全阐明。目前西医治疗CVA需长期维持用药,且停药后易复发,因此越来越多的研究者开始关注中药通过多途径、多靶点治疗CVA,并发现中药具有减少病情复发次数以及缩短疗程等优势。本文就CVA的发病机制及中西药疗效的研究进展进行综述。Cough variant asthma(CVA)is a type of asthma with chronic persistent cough as the main clinical manifestation.Its airway inflammation mechanism is complicated,and the pathophysiological mechanism has not been fully elucidated.At present,Western medicine therapy of CVA requires long-term maintenance medication,and it is easy to relapse after stopping the medication.Therefore,more and more researchers have begun to pay attention to the ability of traditional Chinese medicine on treating CVA through multiple channels and multiple targets.It has been found that traditional Chinese medicine has the advantages of reducing the number of recurrence and shortening the course of treatment.This article reviews the pathogenesis of CVA and the progress of therapeutic effect of traditional Chinese medicine and western medicine.

关 键 词：哮喘 咳嗽变异性哮喘 发病机制 中西药 综述 

分 类 号：R562.25[医药卫生—呼吸系统]