血浆致动脉硬化指数对2型糖尿病患者冠心病的预测价值  

The value of atherogenic index of plasma in predicting coronary heart disease in type 2 diabetic patients

作　　者：汪蕾[1] 蔡濛 韩昊[1] 孙华毅[1] WANG Lei;CAI Meng;HAN Hao;SUN Huayi(Department of Geriatrics,Beijing Jishuitan Hospital,Beijing 100031,China)

机构地区：[1]北京积水潭医院干部科,100031

出　　处：《心肺血管病杂志》2021年第7期675-678,共4页Journal of Cardiovascular and Pulmonary Diseases

摘　　要：目的:探究血浆致动脉硬化指数(AIP)与其他传统的血脂指标在预测糖尿病患者冠心病方面的价值。方法:入选2018年9月至2019年4月期间,于我院行冠状动脉造影检查并明确诊断2型糖尿的3278例患者。根据是否诊断冠心病将患者分为冠心病组(n=2052)和对照组(n=1226)。采用Logistic多因素比例风险回归模型探究AIP及其余血脂指标在糖尿病患者冠心病预测中的价值。结果:总人群的冠心病发病率为62.6%,整体人群的AIP为0.33。Pearson相关分析显示:AIP与其他传统的血脂指标存在相关性。多因素Logistic回归分析显示AIP是2型糖尿病患者冠心病的危险因素,预测价值优于其他传统的血脂指标,我们使用多个模型对结果进行验证。结论:AIP是糖尿病患者发作冠心病强有力的预测指标,预测价值优于传统血脂指标。Objective:To explore the value of atherogenic index of plasma(AIP)and other traditional lipid indexes in predicting coronary heart disease(CHD)in diabetic patients.Methods:A total of 3278 patients who underwent coronary angiography and had a definite diagnosis of type 2 diabetes in our hospital from September 2018 to April 2019 were enrolled.Patients were divided into CHD group(n=2052)and control group(n=1226)according to coronary angiography.Logistic multivariate proportional risk regression model was used to explore the value of AIP and its residual lipids in predicting CHD in diabetic patients.Results:The incidence of coronary heart disease was 62.60%and the plasma arteriosclerosis index was 0.33 in the whole population.Pearson correlation analysis showed that AIP was correlated with (TG,TC,LDL-C,HDL-C,non-HDL-C)of other lipid indexes.Multivariate logistic regression analysis showed that AIP was an independent risk factor for CHD in patients with type 2 diabetes mellitus,which was verified by multiple models and was superior to other traditional lipid indicators.Conclusions:AIP is a powerful independent predictor of CHD in diabetic patients,and its predictive value is better than that of traditional blood lipid indexes.

关 键 词：血脂代谢异常 糖尿病 冠心病 

分 类 号：R54[医药卫生—心血管疾病]