宿州市新冠肺炎疫情不同防控阶段核酸检测结果分析  

Analysis of the nucleic acid detection findings of COVID-19 in different prevention stage in Suzhou City

作　　者：胡雪影[1] 张玲[1] 李垚 陈樱玮 赵娟娟[1] HU Xue-ying;ZHANG Ling;LI Yao;CHEN Ying-wei;ZHAO Juan-juan(Suzhou Center for Disease Control and Prevention,Suzhou 234000,Anhui Province,China)

机构地区：[1]宿州市疾病预防控制中心,安徽宿州234000

出　　处：《热带病与寄生虫学》2021年第4期210-213,共4页Journal of Tropical Diseases and Parasitology

摘　　要：目的在新冠肺炎疫情不同阶段采取不同核酸检测策略,比较新冠病毒核酸检测结果差异,为调整防控措施提供科学依据。方法2020年1月22日-2月29日采集宿州市重点人群的咽拭子和痰液样本,利用实时荧光RT-PCR法检测新型冠状病毒核酸,比较不同防控阶段新冠病毒核酸检测结果差异。结果采集重点人群704人的1182份样本,其中46人的59份样本检测出新冠病毒核酸,样本阳性检出率4.99%(59/1182),最终确诊41例新冠肺炎病例、5例无症状感染者。新冠病毒核酸样本阳性检出率最高阶段为疫情初期,高达14.81%(12/81),其次是第二阶段(6.17%,24/389)和第三阶段(5.71%,22/385),最低为第四阶段(0.31%,1/327)。样本阳性检出率最高人群为有湖北省旅居史人员,为10.13%(31/306),其次是密切接触者3.85%(28/727),本地发热门诊留观患者中未检出阳性。结论宿州市在新冠肺炎疫情发展不同阶段及时调整核酸检测策略,为有效控制疫情的发展提供强有力的保障;在加强对中高风险地区人员、密切接触者等重点人群检测时,应尽可能增加样本采集次数,减少漏检。Objective To compare the diversity of nucleic acid testing findings of COVID-19 in different prevention stages for scientific evidences to develop reasonable prevention and control strategies.Methods Pharyngeal swabs and sputum samples were obtained in the key population in Suzhou from January 22 to February 29,2020,and detected for the nucleic acid specific to COVID-19 using real-time RT-PCR.Then the testing results were compared among the samples tested in different prevention stages.Results A total of 1182 samples were collected from 704 suspected subjects,in whom positive novel coronavirus nucleic acid was found in 46 subjects out of the 59 samples.The positive detection rate was 4.99%(59/1182).Forty-one were finally confirmed as COVID-19,and 5 as asymptomatic infection.The highest positive rate of nucleic acid for COVID-19 was 14.81%(12/81)in the early stage of the epidemic,followed by 6.17%(24/389)in the second stage and 5.71%(22/385)in the third stage,and the lowest positive rate was in the fourth stage(0.31%,1/327).The highest positive rate was seen in subjects with history of travelling or short-term stay in Hubei Province(10.13%,31/306),followed by close contacts(3.85%,28/727).Positive nucleic acid was not detected in local residents in observation at the outpatient due to fever.Conclusion Nucleic acid detection strategy was timely adjusted at different stages of COVID-19 endemic in Suzhou,which has ensured effective implementation of the prevention and control measures.However,sampling frequencies for the nucleic acid should be increased as many as possible in the key population including those from medium and high risk areas or close contacts,so as to reduce missed detection.

关 键 词：新型冠状病毒 核酸检测 宿州市 

分 类 号：R563.1[医药卫生—呼吸系统]