慢性萎缩性胃炎伴上皮内瘤变人群中医体质分布研究  

Study on Distribution of Chinese Medicine Constitutions in Chronic Atrophic Gastritis Patients with Intraepithelial Neoplasia

作　　者：叶春荣[1] 邹声颖 付肖岩[1] 黄灵珊 YE Chun-rong;ZOU Sheng-yin;FU Xiao-yan;HUANG Ling-shan(Department of Spleen and Stomach Diseases,Second People's Hospital Affiliated to Fujian University of Traditional Chinese Medicine,Fuzhou,350000)

机构地区：[1]福建中医药大学附属第二人民医院脾胃科,福州350000

出　　处：《中国中西医结合杂志》2021年第8期907-911,共5页Chinese Journal of Integrated Traditional and Western Medicine

基　　金：福建中医药大学“中医脾胃优势特色学科”建设项目(No.X2019024-学科)。

摘　　要：目的分析慢性萎缩性胃炎(CAG)伴上皮内瘤人群中医体质分布规律。方法回顾性分析2015年2月1日—2017年12月31日在福建中医药大学附属第二人民医院门诊及体检中心行胃镜检查的CAG伴上皮内瘤变受试者及单纯CAG受试者资料,将240例CAG伴上皮内瘤变受试者作为研究组,240例单纯CAG受试者作为对照组,收集患者一般信息、发病部位、中医体质结果等信息,分析不同年龄CAG伴上皮内瘤变发生率与性别的关系,分析性别、年龄、CAG伴上皮内瘤变发生部位与中医体质分布情况的关系,比较CAG伴上皮内瘤变和单纯CAG的中医体质分布情况。结果 240例CAG伴上皮内瘤变患者,不同年龄组CAG伴上皮内瘤变发生率差异有统计学意义(P<0.05),56~65岁年龄段发病多见。CAG伴上皮内瘤变体质分布(兼挟体质纳入其中):血瘀质27例,湿热质100例,气郁质60例,阴虚质33例,痰湿质38例,气虚质45例,阳虚质48例,平和质5例,特禀质5例,以湿热质为主。男性人群以湿热质为主,其次是痰湿质和气郁质;女性人群中以气郁质、气虚质为主,其次是阳虚质。湿热质(11.6%)好发于45~55岁年龄段,气郁质(7.8%)、痰湿质(4.4%)和气虚质(5.3%)好发于56~65岁年龄段,阴虚质(3.6%)、阳虚质(6.6%)好发于>65岁年龄段。CAG伴上皮内瘤变质发生部位以胃窦为主,其次是胃体、胃角,发生部位和体质分布差异无统计学意义(P>0.05)。CAG伴上皮内瘤变人群以湿热质为主,其次是气郁质,然后是阳虚质和气虚质。单纯萎缩性胃炎也是以湿热质为主,其次是阳虚质、气虚质、气郁质。两组间体质分布差异有统计学意义(P<0.05)。结论 CAG伴上皮内瘤变人群中,男性发病率较女性高,发病年龄段中老年人多见,男性人群体质以湿热质为多,女性人群以气郁质、气虚质为主。发病部位与中医体质无明显相关性,CAG伴上皮内瘤变和单纯CAG体质分布具有明显差异。Objective To analyze the distribution laws of Chinese medicine(CM)constitutions in chronic atrophic gastritis(CAG)patients with intraepithelial neoplasia. Methods Retrospective analysis of CAG patients with intraepithelial neoplasia and simple atrophic gastritis in Outpatients Department and Physical Examination Center of Second People’s Hospital Affiliated to Fujian University of Traditional Chinese Medicine from February 1,2015 to December 31,2017 was performed. A total of 240 CAG patients with intraepithelial neoplasia and 240 simple CAG patients were recruited as the study group and the control group respectively. The general information,the position of the disease,and the results of CM constitutions were collected. The relationships between the incidence of CAG with intraepithelial neoplasia and sex were observed in different ages groups. And the relationships between sex/age/the site of CAG with intraepithelial neoplasia and the distribution of CM constitutions were observed. The distribution of CM constitutions of CAG and CAG patients with intraepithelial neoplasia were analyzed and compared. Results In 240 cases of CAG with intraepithelial neoplasia,the incidence of CAG patients with intraepithelial neoplasia was different in different ages groups(P<0.05). It was more often seen in 56~65 years old. The constitution distribution(the mixture is incorporated)included blood stasis(27 cases),damp-heat(100 cases),qi-stagnation(60 cases),yin-deficiency(33 cases),phlegm-dampness(38 cases),qi-deficiency(45 cases),yang-deficiency(48 cases),calmness(5 cases),and temperament(5 cases). It’s mostly moist and hot. The male population was dominated by damp-heat,phlegm-dampness,and qi-stagnation,while the female population was dominated by qi-stagnation and qi-deficiency,followed by yang-deficiency. Dampness-heat was liable to those 45-55 years old(11.6%),qi-stagnation(7.8%),phlegmdampness(4.4%). Qi-deficiency(5.3%)was liable to those 55-65 years old. Yin-deficiency(3.6%)and yangdeficiency(6.6%)were liable to those ol

关 键 词：萎缩性胃炎 上皮内瘤变 中医体质 

分 类 号：R259[医药卫生—中西医结合]