血小板计数、D-D二聚体、纤维蛋白原、红细胞计数在急性肺栓塞患者危险分层评估中的应用价值  

Application value of PLT,D-D,FBG and RBC in risk stratification assessment of patients with acute pulmonary embolism

作　　者：郑璐 ZHENG Lu(Emergency Department,Quzhou Hospital Affiliated to Wenzhou Medical University(Quzhou People's Hospital),Quzhou,Zhejiang 324000,China)

机构地区：[1]温州医科大学附属衢州医院衢州市人民医院,浙江衢州324000

出　　处：《中国卫生检验杂志》2021年第15期1868-1871,共4页Chinese Journal of Health Laboratory Technology

摘　　要：目的探讨PLT、D-D、FBG、RBC在急性肺栓塞患者危险分层评估中的应用价值。方法回顾性分析221例急性肺栓塞患者的临床资料,根据危险分层标准将患者分为低危组135例和中高危组86例,比较2组患者一般资料,分析实验室指标与危险分层的关系。结果中高危组患者PLT、FBG水平明显低于低危组(P<0.05),RBC、HCT、D-D水平明显高于低危组(P<0.05);Logistic回归分析显示,PLT、RBC、FBG、D-D是影响急性肺栓塞患者危险分层的主要因素(P<0.05),HCT与急性肺栓塞危险分层无显著相关性(P>0.05);ROC曲线分析显示,PLT、RBC、FBG、D-D以及四者联合检测评估急性肺栓塞患者风险分层的AUC分别为0.631、0.679、0.630、0.693、0.838,四者联合的评估价值明显高于PLT、RBC、FBG、D-D单一指标(P<0.05)。结论PLT、FBG、RBC在急性肺栓塞患者危险分层评估方面均有一定价值,其中四者联合评估的价值最高,可用于评估危险分层的辅助评估指标。Objective To explore the value of PLT,D-D,FBG and RBC in risk stratification assessment of patients with acute pulmonary embolism.Methods The clinical data of 221 patients with acute pulmonary embolism were retrospectively analyzed.According to risk stratification criteria,the patients were divided into low-risk group(135 cases)and high-risk group(86 cases).The general data of the two groups were compared,and the relationship between laboratory indicators and risk stratification was analyzed.Results The levels of PLT and FBG in middle and high risk groups were significantly lower than those in low risk group(P<0.05),and the levels of RBC,HCT and D-D were significantly higher than those in low risk group(P<0.05).Logistic regression analysis showed that PLT,RBC,FBG and D-D were the main factors affecting the risk stratification of acute pulmonary embolism(P<0.05),while HCT had no significant correlation with the risk stratification of acute pulmonary embolism(P>0.05).ROC curve analysis showed that the AUC of PLT,RBC,FBG,D-D and four com⁃bined tests to assess the risk stratification of patients with acute pulmonary embolism were 0.631,0.679,0.630,0.693,0.838,respectively.The evaluation value of the combination of four indexes was significantly higher than that of any single PLT,RBC,FBG and D-D index(P<0.05).Conclusion PLT,FBG and RBC have certain value in the risk stratification assessment of patients with acute pulmonary embolism,among which the combined assessment of the three has the highest value and can be used as auxiliary assessment indicators for the risk stratification assessment.

关 键 词：急性肺栓塞 危险分层 血小板计数 红细胞计数 纤维蛋白原 

分 类 号：R563.5[医药卫生—呼吸系统]