有机化学综合实验:基于联二萘酚手性聚集诱导发光分子的合成、表征及性质研究  

Comprehensive Experiment in Organic Chemistry: Synthesis, Characterization and Properties of BINOL-Based Chiral Compound with Aggregation-Induced Emission Characteristics

作　　者：赵娜 李楠 ZHAO Na;LI Nan(School of Chemistry&Chemical Engineering,Shaanxi Normal University,Xi'an 710119,China)

机构地区：[1]陕西师范大学化学化工学院,陕西西安710119

出　　处：《化学教育（中英文）》2021年第16期60-65,共6页Chinese Journal of Chemical Education

基　　金：陕西师范大学优秀青年学术骨干资助计划(18QNGG007)。

摘　　要：将前沿科学成果引入大学有机化学综合实验课中,设计了基于联二萘酚手性聚集诱导发光分子的合成、表征及性质研究的有机化学综合实验。通过本实验,学生将掌握几类经典的有机反应,包括酚羟基保护、芳基甲酰化及缩合等反应的基本原理及操作,熟悉核磁共振、质谱等结构表征手段以及紫外-可见吸收光谱、荧光光谱以及圆二色光谱等性质表征技术,了解聚集诱导发光现象及机理。本实验综合了多种有机反应及性质表征技术,有利于提升学生的综合实验能力、科学研究思维并激发学生对科学研究的兴趣。In this paper, the cutting edge result was introduced into the comprehensive experiment in organic chemistry. We designed a comprehensive experiment on the synthesis, characterization and properties of BINOL-based chiral compound with aggregation-induced emission characteristics. Based on this experiment, the students will learn several basic organic transformations, such as protection of phenol hydroxyl groups, formylation and condensation reactions. Meanwhile, they will characterize the chemical structure of this chiral compound by using nuclear magnetic resonance and mass spectroscopies, and investigate its optical properties by employing UV-Vis, emission and circular dichroism spectroscopies. This experiment will help students to have a better understanding about the phenomenon and mechanism of aggregation-induced emission. This experiment combined various organic reactions and characterization methods, which is conducive to systematically improving the experimental ability, scientific research ability and inspiring the interests in scientific research of students.

关 键 词：有机化学综合实验 聚集诱导发光 手性 联二萘酚 

分 类 号：O621.3-4[理学—有机化学] G642.423[理学—化学]