蝉花多糖对肉鸡脂质代谢和免疫功能的影响  

Effects of Cordyceps cicadae polysaccharide on lipid metabolism and immune function of chicken

作　　者：李瑞萍 刘长国 张硕 董丽艳[3] 王秋霞[3] 徐时湘 李国勤[2] 田勇[2] 柴一秋[4] 刘素贞[3] 卢立志[2] LI Ruiping;LIU Changguo;ZHANG Shuo;DONG Liyan;WANG Qiuxia;XU Shixiang;LI Guo-qin;TIAN Yong;CHAI Yiqiu;LIU Suzhen;LU Lizhi(College of Animal Science Zhejiang A&F University,Hangzhou 311300,China;Institue of Animal Husbandry and Veterinary Medicine Zhejiang Academy of Agricultural Sciences,Hangzhou 310021,China;College of Animal Science,Wenzhou Vocational College of Science and technology Wenzhou,Zhejiang 325000,China;Key Laboratory of Entomogenous Fungus Resources Research and Development of Wenzhou,Zhejiang Institute of Subtropical Crops,Wenzhou,Zhejiang 325005,China)

机构地区：[1]浙江农林大学动物科技学院,浙江杭州311300 [2]浙江省农业科学院畜牧兽医研究所,浙江杭州310021 [3]温州科技职业学院动物科学学院,浙江温州325000 [4]浙江省亚热带作物研究所温州市虫生真菌资源研究与开发重点实验室,浙江温州325005

出　　处：《中国兽医学报》2021年第8期1598-1603,共6页Chinese Journal of Veterinary Science

基　　金：浙江省公益基础研究资助项目“蝉花虫草提取物在鸡无抗生素饲养中的研究和应用”(LGN19C170004);浙江省农科院仙居鸡产业团队科技特派员资助项目。

摘　　要：为探究在雏鸡生长中添加蝉花多糖对鸡脂质代谢及免疫功能的影响,试验选取270只雁荡麻鸡,随机分成6组,公母各半,每组3个重复,每个重复15只。每只鸡分别于11~17日龄和25~31日龄灌服(1次/d),其中Ⅰ组(非免疫)和Ⅱ组(免疫)各灌服生理盐水,Ⅲ组灌服杆菌肽锌(50 mg/kg),Ⅳ~Ⅵ组分别灌服25,50,100 mg/kg的蝉花多糖,每只0.5 mL,试验期42 d。结果显示:Ⅳ~Ⅵ组血清中TC含量显著低于Ⅲ组(P<0.05),Ⅳ组TC含量和Ⅴ组TP含量显著优于Ⅰ~Ⅲ组(P<0.05),Ⅵ组TP含量和Ⅴ组GLB含量显著高于Ⅰ、Ⅱ组(P<0.05),Ⅵ组GLB含量和Ⅳ组TG含量显著优于Ⅰ组(P<0.05);Ⅳ~Ⅵ组脾脏指数和法氏囊指数高于Ⅲ组(P>0.05);Ⅴ组血清中免疫球蛋白A(IgA)含量显著高于Ⅰ、Ⅱ组,Ⅴ组血清中补体C3(C3)含量显著高于Ⅰ~Ⅲ组(P<0.05),Ⅳ组血清中补体C4(C4)含量显著高于Ⅰ、Ⅲ组(P<0.05);Ⅴ组血清中干扰素-γ(IFN-γ)含量、Ⅳ组血清中肿瘤坏死因子-α(TNF-α)含量及Ⅳ~Ⅵ组血清中白介素-2(IL-2)含量均显著高于Ⅱ、Ⅲ组(P<0.05),Ⅴ组血清中TNF-α含量显著高于Ⅱ、Ⅲ组(P<0.05),Ⅴ、Ⅵ组血清中白介素-4(IL-4)含量显著高于Ⅱ组(P<0.05)。结果表明,蝉花多糖能提高雁荡麻鸡脂质代谢和免疫能力。本试验条件下,蝉花多糖中剂量组(50 mg/kg)效果最佳。The purpose of this study was to investigate the effects of adding Cordyceps cicadae polysaccharide in feed on lipid metabolism and immune function of chicken.In this experiment,270 Yandang Ma-chicken,half male and half female,were randomly divided into 6 groups with 3 replicates in each group and 15 chickens in each replicate.In 42-day test period,chickens in 11-17 and 25-31 day-old in every group were drenched with different solution,every chicken with 0.5 mL,includingⅠgroup(non-immune)with normal saline,Ⅱgroup(immune)with normal saline,Ⅲgroup with bacitracin zinc(50mg/kg),Ⅳ-Ⅵgroups with 25,50,100mg/kg Cordyceps cicadae polysaccharide respectively.The results showed that the TC in serum ofⅣ-Ⅵgroups significantly lowered thanⅢgroup(P<0.05).The level ofⅣgroup TC andⅤgroup TP were significantly higher thanⅠ-Ⅲgroups(P<0.05).TP content in groupⅥand GLB content in groupⅤwere significantly higher thanⅠandⅡgroups(P<0.05).The levels of GLB in groupⅥand TG in groupⅣwere significantly higher thanⅠgroup(P<0.05).The index of spleen and bursa of fabricius inⅣ-Ⅵgroups were higher thanⅢgroup(P>0.05).The serum immunoglobulin A(IgA)content inⅤgroup was significantly higher than that ofⅠandⅡgroups.The serum C3content inⅤgroup was significantly higher thanⅠ-Ⅲgroups(P<0.05).The serum C4content inⅣgroup was significantly higher thanⅠ,Ⅲgroups(P<0.05).The serum interferon-γ(IFN-γ)content inⅤgroup,the serum tumor necrosis factor-α(TNF-α)content in B group,the serum interleukin-2(IL-2)content inⅣ-Ⅵgroups,were significantly higher than that ofⅡandⅢgroups(P<0.05).The serum TNF-αcontent inⅤgroup was significantly higher than that ofⅡandⅢgroups(P<0.05).The serum interleukin-4(IL-4)inⅤandⅥgroups were significantly higher than that of groupⅡ(P<0.05).The results indicated that the Cordycepscicadaepolysaccharide can improve lipid metabolism and immunity of Yandang Ma-chicken.In this experiment,the medium dose group(50mg/kg)of Cordyceps cicadae polysaccharid

关 键 词：蝉花多糖 雁荡麻鸡 脂质代谢 免疫功能 

分 类 号：S831.5[农业科学—畜牧学] S816.7[农业科学—畜牧兽医]