低分子肝素联合阿司匹林治疗重度子痫前期对患者血浆蛋白、尿蛋白水平及预后的影响  

The effect of low molecular weight heparin combined with aspirin in the treatment of hypertension in pregnancy on the level of plasma protein,urine protein and prognosis

作　　者：黄锡欢[1] 徐婉卿 黎文英[1] HUANG Xihuan;XU Wanqing;LI Wenying(Department of Obstetrics,Zhongshan Boai Hospital,Zhongshan,Guangdong,528400,China)

机构地区：[1]中山市博爱医院产科,广东中山528400

出　　处：《当代医学》2021年第25期60-62,共3页Contemporary Medicine

摘　　要：目的探讨采用低分子肝素+阿司匹林治疗重度子痫前期患者的效果。方法选取2016年3月至2019年10月本院收治的重度子痫前期患者100例作为研究对象,根据红蓝双色球分配原则分为实验组与参照组,各50例。参照组采用阿司匹林治疗,实验组采用低分子肝素+阿司匹林治疗,比较两组治疗效果及不良妊娠结局发生率。结果与治疗前相比,治疗后,两组尿蛋白、血浆白蛋白、血浆总蛋白水平均明显改善,且实验组均优于参照组(P<0.05);实验组预后不良妊娠结局发生率低于参照组(P<0.05)。结论采用低分子肝素+阿司匹林治疗重度子痫前期患者效果显著,患者预后较好,值得临床推广。Objective To investigate the effect of low molecular weight heparin+aspirin in the treatment of severe preeclampsia.Methods 100 patients with severe preeclampsia admitted to our hospital from March 2016 to October 2019 were selected as the research subjects.They were divided into experimental group and control group according to the distribution principle of red and blue spheres,with 50 cases in each group.The control group was treated with aspirin,the experimental group was treated with low molecular heparin+aspirin treatment,and the therapeutic effects and the incidence of adverse pregnancy outcomes were compared between the two groups.Results Compared with before treatment,the levels of urinary protein,plasma albumin and total protein were significantly improved after treatment,and the experimental group were better than the control group(P<0.05);the incidence of adverse pregnancy outcomes in the experimental group was lower than that in the control group(P<0.05).Conclusion The treatment of severe preeclampsia with low molecular weight heparin+aspirin is effective,and the prognosis is good,which is worth clinical promotion.

关 键 词：重度子痫前期 预后 血浆白蛋白 尿蛋白 

分 类 号：R714.244[医药卫生—妇产科学]