新生儿危重症肺动脉瓣狭窄介入治疗分析  

Analysis of interventional treatment for neonatal critical pulmonary stenosis

作　　者：李博宁[1] 刘琮[1] 欧振恒 刘麟[1] 谢颖[1] 辛颖 李薇玢[1] 姚静[1] 王威[1] 时晓侠 刘艳华 Li Boning;Liu Cong;Ou Zhenheng;Liu Lin;Xie Ying;Xin Ying;Li Weifen;Yao Jing;Wang Wei;Shi Xiaoxia;Liu Yanhua(Department of Cardiology,Shenzhen Children′s Hospital,Shenzhen 518038,Guangdong Province,China)

机构地区：[1]深圳市儿童医院心血管内科,广东深圳518038

出　　处：《中华实用儿科临床杂志》2021年第14期1074-1076,共3页Chinese Journal of Applied Clinical Pediatrics

基　　金：深圳市三名工程(SZSM201612057);深圳市战略性新兴产业发展专项基金"创业链+产业链"融合专项扶持技术(20180309175312565)。

摘　　要：目的评估新生儿危重症肺动脉瓣狭窄(NCPS)患儿介入治疗的效果。方法总结分析2016年1月至2019年12月在深圳市儿童医院心血管内科完成的12例经皮肺动脉瓣球囊扩张术(PBPV)NCPS患儿病例资料。收集其临床资料包括经胸心脏超声(TTE)、经皮血氧饱和度(SPO_(2))、介入手术相关数据以及随访结果等。结果12例NCPS患儿行PBPV术均取得成功。术后导管测右心室与肺动脉压差为8~35 mmHg[平均(20±7)mmHg,1 mmHg=0.133 kPa]。术后SPO_(2)为74%~100%[(93.0±5.9)%]。3例NCPS患儿行B-T分流术。1例NCPS患儿术中出现室上性心动过速。12例NCPS患儿均未死亡。结论介入治疗NCPS效果较好,可作为NCPS的首选治疗方案,部分NCPS患儿需行心B-T分流或动脉导管未闭支架植入术。Objective To evaluate the effectiveness of interventional treatment for neonatal critical pulmonary stenosis(NCPS).Methods Clinical data of 12 neonates with NCPS who received percutaneous balloon pulmonary valvuloplasty(PBPV)from January 2016 to December 2019 in Department of Cardiology,Shenzhen Children′s Hospital were summarized and analyzed.The collected data included transthoracic echocardiography(TTE),percutaneous oxygen saturation(SPO_(2)),relevant data on interventional surgery,and follow-up results.Results All 12 neonates with NCPS received PBPV successfully.The postoperative pressure difference between the right ventricle and the pulmonary artery ranged from 8 to 35 mmHg[(20±7)mmHg,1 mmHg=0.133 kPa].The postoperative SPO_(2) ranged from 74%-100%[(93.0±5.9)%].Three neonates with NCPS received Blalock-Taussig(B-T)shunt.One neonate with NCPS developed supraventricular tachycardia during the operation.There was no death for these 12 neonates with NCPS.Conclusions Interventional treatment of neonates with NCPS could achieve a better effect and be employed as the first treatment option.Some neonates with NCPS would require cardiac B-T shunt or patent ductus arteriosus stent implantation.

关 键 词：新生儿危重症肺动脉瓣狭窄 介入 球囊扩张 

分 类 号：R722.1[医药卫生—儿科]