前列腺癌患者根治性手术后阴茎尺寸改变及相关影响因素  

Changes in the penis size of prostate cancer patients after radical prostatectomy and its influencing factors

作　　者：宿恒川 顾晓峰 朱耀 戴波 秦晓健 林国文 沈益君 叶定伟 SU Heng-chuan;GU Xiao-feng;ZHU Yao;DAI Bo;QIN Xiao-jian;LIN Guo-wen;SHEN Yi-jun;YE Ding-wei(Department of Urology,Shanghai Cancer Center of Fudan University,Shanghai 200032,China;Department of Oncology,Shanghai Medical College,Fudan University,Shanghai 200032,China)

机构地区：[1]复旦大学附属肿瘤医院泌尿外科,上海200032 [2]复旦大学医学院肿瘤学系,上海200032

出　　处：《中华男科学杂志》2021年第6期522-525,共4页National Journal of Andrology

摘　　要：目的:探讨前列腺癌患者行根治性前列腺切除术后阴茎尺寸变化规律及可能的影响因素。方法:回顾性分析接受根治性前列腺切除术的45例患者,手术均为同1人完成,对患者术前及术后2周拔除导尿管时阴茎尺寸予以测量,以了解阴茎尺寸变化规律,同时对患者行IIEF-5问卷调查,以了解患者术前一般情况以及对于阴茎康复的接受态度,分析影响阴茎尺寸变化的因素。结果:同术前相比,手术后拉伸阴茎长度,松弛阴茎长度及阴茎周径均出现下降,差异具有统计学意义(P均<0.05),其中拉伸阴茎长度萎缩(1.92±0.12)cm,松弛阴茎长度萎缩(1.13±0.09)cm,阴茎周长萎缩(0.43±0.08)cm。患者年龄同松弛阴茎长度改变存在相关性(P=0.042),而患者其他特征同阴茎尺寸改变无相关性。术后中重度ED患者居多例26(57.7%),术前性功能越好的患者对于阴茎康复的态度越积极,也更容易寻求治疗3例(75.0%)。结论:根治性前列腺切除术后,阴茎尺寸会出现显著性下降,患者年龄同手术后松弛阴茎尺寸改变存在相关性,术前性功能越好的患者对于阴茎康复的态度越积极,更易寻求治疗。Objective:To investigate the changes in the size of the penis after radical prostatectomy(RP)and the possible influencing factors.Methods:This study included 45 cases of RP for PCa performed by the same surgeon from January to June 2019.Before and at 2 weeks after surgery,we measured the stretched penile length(SPL),flaccid penile length(FPL)and penile circumference of the patients.We conducted an IIEF-5 questionnaire investigation on the preoperative characteristics of the patients and their attitudes towards postoperative penile rehabilitation.We also analyzed the factors associated with the postoperative changes in the size of the penis.Results:Compared with the baseline,the postoperative SPL([9.72±1.87]vs[7.80±1.57]cm,P=0),FPL([6.26±1.14]vs[5.13±1.10]cm,P=0)and penile circumference([7.69±0.83]vs[7.26±0.78]cm,P=0.012)were decreased significantly,by(1.92±0.12)cm,(1.13±0.09)cm and(0.43±0.08)cm,respectively.The age of the patients was significantly correlated with the change of the FPL(P=0.042),but not the other factors with the change of the penile size.Twenty-six(57.7%)cases of severe and moderate ED were observed in the patients postoperatively.Those with better preoperative sexual function took a more positive attitude towards penile rehabilitation and treatment postoperatively(n=3,75.0%).Conclusion:The penile size of the PCa patient is decreased markedly after radical prostatectomy,with a significant correlation between the patient’s age and the postoperative change of the flaccid penile length.The patients with better preoperative sexual function are more likely to seek penile rehabilitation and treatment postoperatively.

关 键 词：前列腺癌 根治性前列腺切除术 阴茎 长度 周径 变化 影响因素 

分 类 号：R697.1[医药卫生—泌尿科学] R737.35[医药卫生—外科学]