Determination of Diphenylamine in Gunshot Residue by HPLC‑MS/MS  

作　　者：Hongcheng Mei Yangke Quan Wenhao Wang Hong Zhou Zhanfang Liu Huixia Shi Peng Wang 

机构地区：[1]Institute of Forensic Science,Ministry of Public Security,1College of Forensic Science,People’s Public Security University of China,Beijing [2]Xianyang Public Security Bureau,Shanxi,China

出　　处：《Journal of Forensic Science and Medicine》2016年第1期18-21,共4页法庭科学与法医学杂志（英文）

基　　金：This study was supported by the Basal Research Fund Program of Institute of Forensic Science,Ministry of Public Security,China(2014JB006).

摘　　要：A high performance liquid chromatography tandem mass spectrometry/mass spectrometry(HPLC-MS/MS)protocol was developed for the determination of diphenylamine(DPA).Four productions of DPA were selected for qualitative assay and the peak area of the main product ion for quantitation.By means of separation using an Agilent Extend-C18 column(CA,USA)(150 mm×4.6 mm,5μm)with methanol‑water(90:10)as the mobile phase,DPA was detected by electrospray ionization(ESI)tandem mass spectrometry in positive mode.The linearity of the peak area versus concentration ranged 5‑500 ng/mL,r^(2)=0.9978.The limit of detection(S/N=3)of this method was 0.3 ng/mL.This method is applicable for the determination of DPA in gunshot residue.

关 键 词：DIPHENYLAMINE gunshot residue high performance liquid chromatography-mass spectrometry/mass spectrometry 

分 类 号：O62[理学—有机化学]