2020版Basel免疫抑制药物依从性评估量表的跨文化调适及信效度检验  

Cross-cultural adaptation and validation of the 2020 Basel Assessment of Adherence to Immunosuppressive Medications Scale

作　　者：刘宁 刘佳 钟竹青[1,2] 王潇 Liu Ning;Liu Jia;Zhong Zhuqing;Wang Xiao(Xiangya School of Nursing,Central South University,Changsha 410013,China)

机构地区：[1]中南大学湘雅护理学院,湖南长沙410013 [2]中南大学湘雅三医院

出　　处：《护理学杂志》2021年第16期6-9,共4页Journal of Nursing Science

基　　金：国家自然科学基金青年项目(71904209);湖南省卫生与健康委员会一般项目(202114051600)。

摘　　要：目的对2020版Basel免疫抑制药物依从性评估量表进行文化调适,为我国器官移植术后患者用药依从性评估提供有效工具。方法在取得原量表作者授权后,根据指南和临床实践对2020英文版Basel免疫抑制药物依从性评估量表进行跨文化调适。采用调适后的中文版量表调查肝、肾移植术后患者475例,分析量表的信效度。结果2020中文版Basel免疫抑制药物依从性评估量表共10个条目,Cronbach'sα系数为0.755,重测信度系数为0.876,量表水平及条目水平的内容效度指数均为1.000。探索性因子分析共提取4个公因子,解释总变异的83.507%。验证性因子分析显示,χ^(2)/df=3.64,RMR=0.01,GFI=0.93,AGFI=0.86,RMSEA=0.11,CFI=0.96,TLI=0.94。结论2020中文版Basel免疫抑制药物依从性评估量表与原量表的信效度相当,各条目使用方便,易于理解,可用于测量我国器官移植术后患者的用药依从性。Objective To adapt the 2020 Basel Assessment of Adherence to Immunosuppressive Medications Scale(BAASIS)accor-ding to culture,and to provide effective tool assessing drug compliance of patients after organ transplantation in China.Methods After obtaining permission from the author of the original scale,the 2020 English version of the BAASIS was translated and adapted across cultures according to guidelines and clinical practice.Then a total of 475 patients after liver or kidney transplantation were investigated using the adjusted Chinese version BAASIS,and its reliability and validity were analyzed.Results The final 2020 Chinese version BAASIS was consisted of 10 items,its Cronbach'sαcoefficient was 0.755,the test-retest reliability coefficient was 0.876,and the content validity index of the scale and each item was 1.000.Four common factors were extracted via exploratory factor analysis,which explained 83.507% of the total variance.Confirmatory factor analysis showed that,χ^(2)/df=3.64,RMR=0.01,GFI=0.93,AGFI=0.86,RMSEA=0.11,CFI=0.96,TLI=0.94.Conclusion The 2020 Chinese version BAASIS has the same reliability and validity as the original scale,its items are easy to use and understand,so it can be used to assess medication compliance for the patients after organ transplantation in China.

关 键 词：器官移植 免疫抑制药物 依从性 Basel免疫抑制药物依从性评估量表 文化调适 信度 效度 

分 类 号：R473.6[医药卫生—护理学]