A fundamental study on the fluorescence-quenching effect of nitro groups in tetraphenylethene AIE dyes with electron-withdrawing groups  

作　　者：Cheng-Xiao Zhao Tian Liu Manyi Xu Hao Lin Chong-Jing Zhang 

机构地区：[1]State Key Laboratory of Bioactive Substance and Functions of Natural Medicines and Beijing Key Laboratory of Active Substances Discovery and Drugability Evaluation,Institute of Materia Medica,Peking Union Medical College and Chinese Academy of Medical Sciences,Beijing 100050,China [2]School of Pharmaceutical Science,Shanxi Medical University,Taiyuan 030001,China

出　　处：《Chinese Chemical Letters》2021年第6期1925-1928,共4页中国化学快报（英文版）

基　　金：start-up funding from the State Key Laboratory of Bioactive Substance and Function of Natural Medicines,Institute of Materia Medica,Peking Union Medical College,CAMS Innovation Fund for Medical Sciences(CIFMS)(No.2017-I2M-4-005)。

摘　　要：A nitro group is a common fluorescence quencher,but its quenching efficiency can be easily affected by the surrounding environment.To date,there has been no systematic study on the effects of electronwithdrawing groups on the quenching efficiency of nitro groups.Herein,by virtue of experimental validation and theoretical calculations,we found that strong electron-withdrawing groups,such as pyridinium and dicyanovinyl groups,are detrimental to the quenching effect of nitro groups.Decreasing the electron-withdrawing ability could restore the nitro group’s quenching effect.

关 键 词：FLUORESCENCE Aggregation-induced emission Quenching effect Nitro group 

分 类 号：O657.3[理学—分析化学]