支撑喉镜下二氧化碳激光治疗早期声门型喉癌的临床效果  

Clinical effect of carbon dioxide laser under suspension laryngoscopy in treatment of early glottic carcinoma

作　　者：段飞[1] 陈羿[1] 蔡艳臣[1] 邹辉文[1] DUAN Fei;CHEN Yi;CAI Yan-chen;ZOU Hui-wen(Department of Otorhinolaryngology Head and Neck Surgery,Jiujiang First People′s Hospital,Jiangxi Province,Jiujiang332600,China)

机构地区：[1]江西省九江市第一人民医院耳鼻咽喉头颈外科,江西九江332600

出　　处：《中国当代医药》2021年第24期167-169,共3页China Modern Medicine

基　　金：江西省卫生健康委科技计划项目(20202040)。

摘　　要：目的探讨支撑喉镜下二氧化碳激光治疗早期声门型喉癌的临床效果。方法选取2019年1月—2020年6月九江市第一人民医院收治的30例早期声门型喉癌患者作为研究对象,按照随机数字表法分为对照组(n=15)和治疗组(n=15),对照组采用喉裂开喉局部切除术方法,治疗组采用支撑喉镜下二氧化碳激光方法。比较两组的治疗效果、生活质量、嗓音功能、生存率、复发率。结果治疗组治疗总有效率及生存率高于对照组,差异有统计学意义(P<0.05)。术前两组的生活质量评分比较,差异无统计学意义(P>0.05),术后3个月,治疗组的生活质量评分高于对照组,差异有统计学意义(P<0.05)。术前两组嗓音功能比较,差异无统计学意义(P>0.05);术后3个月,观察组最长发声时间长于对照组,声压级高于对照组,基频微扰低于对照组,差异有统计学意义(P<0.05)。术后3个月,治疗组复发率为6.67%(1/15),低于对照组的46.67%(7/15),差异有统计学意义(P<0.05)。结论早期声门型喉癌以支撑喉镜下二氧化碳激光展开诊疗效果理想,能够将肿瘤精准切除,重复性及安全性较高,最大化降低了因鼻饲管所致机体痛苦的影响,达到真正意义上的微创治疗。Objective To explore the clinical effect of carbon dioxide laser under suspension laryngoscopy in the treatment of early glottic carcinoma.Methods Thirty patients with early glottic laryngeal cancer admitted to the Jiujiang First People′s Hospital from January 2019 to June 2020 were selected as the research subjects and divided into control group(n=15)and treatment group(n=15)according to random number table method.The control group were treated with local laryngectomy for dehiscence,and the treatment group were treated with carbon dioxide laser under suspension laryngoscope.The treatment effect,quality of life,voice function,survival rate and recurrence rate were compared between the two groups.Results The total effective rate and survival rate in the treatment group were higher than those in the control group,and the differences were statistically significant(P<0.05).There was no significant difference in preoperative quality of life scores between the two groups(P>0.05).Three months after operation,the quality of life score of the treatment group was higher than that of the control group,the difference was statistically significant(P<0.05).There was no significant difference in voice function between the two groups before operation(P>0.05).Three months after surgery,the longest vocalization time in the observation group was longer than that in the control group,the sound pressure level was higher than that in the control group,and the fundamental frequency perturbation was lower than that in the control group,the differences were statistically significant(P<0.05).Three months after operation,the recurrence rate of the treatment group was 6.67%(1/15),lower than that of the control group(46.67%,7/15),and the difference was statistically significant(P<0.05).Conclusion The diagnosis and treatment of early glottic cancer using carbon dioxide laser under suspension laryngoscope is ideal.It can accurately remove the tumor,with high repeatability and safety,which minimizes the impact of the body pain caused by the n

关 键 词：支撑喉镜下 二氧化碳激光 早期声门型喉癌 嗓音功能 效果 

分 类 号：R939.65[医药卫生—生药学]