肿瘤患者预防性止吐药物使用规范性分析  

Analysis of Normative Use of Preventive Anti-emetic Drugs in Cancer Patients

作　　者：李雪芹 曲爱美 郭其 LI Xue-qin;QU Ai-mei;GUO Qi(Yantai Affiliated Hospital of Binzhou Medical University,Yantai 264100,China)

机构地区：[1]滨州医学院烟台附属医院,山东烟台264100

出　　处：《中国药物评价》2021年第4期343-346,共4页Chinese Journal of Drug Evaluation

摘　　要：目的:通过对肿瘤患者预防性止吐药物使用分析,为临床合理用药提供参考。方法:利用医院HIS系统,回顾性调查医院肿瘤科2020年1~12月首次接受抗肿瘤治疗的患者医嘱病例875例,对治疗过程中预防性止吐药物使用情况进行评价分析。结果:在调查的875例中,599例符合纳入排除标准,334例(55.76%)存在不合理用药;不合理用药包括联合用药不规范(14.07%)、用药疗程不规范(51.80%)、止吐方案级别选择不规范(34.13%);规范预防组恶心呕吐的控制率明显优于不规范用药组(64.91%VS 48.80%,P<0.05)。结论:我院预防性止吐方案的选择存在不足,临床医师应根据抗肿瘤方案规范性选择止吐方案,降低恶心呕吐的发生,提高患者治疗依从性和生活质量,促进临床合理用药。Objective:By analyzing the preventive anti-emetic drugs in Cancer Patients to provide reference for clinical rational medication.Methods:Using the hospital HIS system to retrospectively investigate 875 patients who received the first anti-tumor treatment in the department of oncology of the hospital from January to December 2020 and analyze the use of preventive anti-emetic drugs during the treatment.Results:Among the 875 cases investigated,599 cases met the inclusion and exclusion criteria,and 334 cases(55.76%)had irregular drug use.Non-standard medication includes non-standard combination medication(14.07%),non-standard medication course(51.80%)and non-standard anti-emetic program level selection(34.13%).The control rate of nausea and vomiting in the standard prevention group was significantly better than that in the non-standard medication group(64.91%vs 48.80%,P<0.05).Conclusion:The choice of preventive anti-emetic plan in our hospital is insufficient.Clinicists should choose the standard plan to stop vomiting according to the anti-tumor regimens to reduce the happening of nausea and vomiting,improve the treatment compliance and the quality of the life of patients,and promote clinical rational use of drugs.

关 键 词：预防性止吐药物 化疗引起恶心呕吐 规范性 肿瘤患者 

分 类 号：R95[医药卫生—药学]