高危型人乳头瘤病毒感染检测及宫颈病变影响因素分析  

Detection of high-risk human papillomavirus infection and analysis of the influencing factors of cervical lesions

作　　者：欧武 曾云[1] 毛毅影 吴丽芳 OU Wu;ZENG Yun;MAO Yi-ying;WU Li-fang(Department of Clinical Laboratory,Huizhou Second Maternal and Child Health Hospital,Huizhou 516001,China)

机构地区：[1]惠州市第二妇幼保健院检验科,广东惠州516001

出　　处：《黑龙江医药科学》2021年第4期34-35,18,共3页Heilongjiang Medicine and Pharmacy

基　　金：广东省惠州市科技计划项目,编号:20170406。

摘　　要：目的:探讨高危型人乳头瘤病毒(HPV)感染检测与宫颈病变的影响因素。方法:选取2019-01~2020-06经1300例宫颈癌筛查及HC2检测阳性的202例患者为研究对象,对202例患者均进行液基薄层细胞学检查(TCT)及阴道镜检查,评价检查结果,同时将HC2阳性者年龄、病毒负荷作为自变量,宫颈病变的具体程度为应变量,做多元回归分析引起宫颈病变的相关影响因素。结果:202例女性中,宫颈病变的程度越重,TCT阳性率越高。202例高危型HPV感染中,年龄、病毒负荷同宫颈病变程度存在密切联系,且病毒负荷影响程度更加明显。结论:高危型HPV感染者病变程度同TCT阳性正相关,年龄及病毒负荷同宫颈病变风险有密切联系。Objective:To explore the risk factors of human papillomavirus(HPV)infection detection and cervical lesions.Methods:Two hundred and two patients with 1300 cervical cancer screening and HC2 positive tests from January 2019 to June 2020 were selected as subjects.All patients underwent liquid-based thin-layer cytology(TCT)and colposcopy,and the examination results were evaluated.At the same time,the age and viral load of HC2 positive patients were taken as independent variables,and the specific degree of cervical lesions was taken as dependent variable.Through multiple regression equation,the related influencing factors of cervical lesions were analyzed.Results:The study found that the more severe the cervical lesions,the higher the positive rate of TCT.Among 202 high-risk HPV infection patients,age and viral load were closely related to the degree of cervical lesions,and the effect of viral load was more obvious.Conclusion:The lesion degree of high-risk HPV patients is positively correlated with the positive TCT,and the age and viral load are closely related to the risk of cervical lesions.

关 键 词：人乳头瘤病毒感染 高危型 感染检测 宫颈病变 影响因素 

分 类 号：R711.32[医药卫生—妇产科学]