常用妇产科抗菌药物的调查分析  

Investigation and Analysis of Commonly Used Antibacterial Drugs in Obstetrics and Gynecology

作　　者：陈玉[1] 王猛[1] CHEN Yu;WANG Meng(Department of Obstetrics,Peopled Hospital of Tanghe County,Nanyang,Henan 473400,China)

机构地区：[1]南阳市唐河县人民医院产科,河南南阳473400

出　　处：《中国药物滥用防治杂志》2021年第4期558-561,共4页Chinese Journal of Drug Abuse Prevention and Treatment

摘　　要：目的:探讨妇产科患者常用的抗菌药物情况,以期为临床合理使用抗菌药物提供参考。方法:回顾性分析2016年1月-2020年12月于该院妇产科出院的360例患者的临床资料,分析出院患者使用抗菌药物的情况。结果:360例患者中使用抗菌药物280例,占77.78%,其中以治疗为目的 220例,占比78.57%;以预防为目的 60例,占比21.43%。抗菌药物使用时间1~10 d,平均使用时间(5.41±0.69)d。使用单味药进行治疗60例,占比21.43%;使用两味药进行联合治疗200例,占比71.43%;使用3味药进行联合治疗20例,占比7.14%。妇产科常用的抗菌药物主要为头孢呋辛、头孢唑林、头孢曲松、阿奇霉素、青霉素钠等,常用口服抗菌药物为阿奇霉素、克拉霉素、阿莫西林、左氧氟沙星、头孢呋辛,常用注射剂型抗菌药物主要为头孢呋辛、头孢唑林、头孢曲松、青霉素钠、奥硝唑。2016年1月—2020年12月妇产科抗菌药物使用强度在31 DDDs左右,抗菌药物使用率在54%左右。结论:该院妇产科抗菌药物合理性基本合格,还应加强对妇产科抗菌药物的监督和管理,提高抗菌药物的安全性,为患者提供最安全的药物保障。Objective: To analyse the application of commonly used antibiotics in obstetrics and gynecology patients, in order to provide a reference for clinical rational application. Methods: Retrospectively analyzed the clinical data of 360 patients discharged from the obstetrics and gynecology department of the hospital from January 2016 to December 2020, and investigated and analyzed the use of antibacterial drugs in the discharged patients. Results: Among 360 patients, 280 patients used antibacterial drugs, accounting for 77.78%, including 220 cases were for treatment, accounting for 78.57%;60 cases were for prevention, accounting for 21.43%. Duration of antibiotic use was 1-10 d, the average using time were(5.41± 0.69) d. Among the 280 patients who used antibacterial drugs, 60 cases were treated with a single medicine, accounting for 21.43%;200 cases were treated with two-medicine, accounting for 71.43%;and 20 cases were treated with three herbs for combined treatment, accounting for 7.14%. The antibacterial drugs commonly used in obstetrics and gynecology were mainly cefuroxime, cefazolin, ceftriaxone, azithromycin, penicillin sodium;the common oral antibacterial drugs in obstetrics and gynecology was azithromycin, clarithromycin, amoxicillin, levofloxacin, and cefuroxime;the common injectable antibacterial drugs in obstetrics and gynecology were mainly cefuroxime, cefazolin, ceftriaxone, penicillin sodium, and ornidazole. In 2016-2020, the use intensity of antibacterial drugs for the whole year was about 31 DDDs and the use rate was about 54%. Conclusion: The hospital’s obstetrics and gynecology antibacterial drugs are basically qualified, and the supervision and management of antibacterial drugs in the obstetrics and gynecology department should be strengthened to improve the safety of antibacterial drugs and provide patients with the safest drugs.

关 键 词：妇产科 抗菌药物 合理用药 细菌耐药 

分 类 号：R95[医药卫生—药学]