后疫情时代的肺移植临床研究发展和未来展望  

Development and prospect of clinical research on lung transplantation in post-COVID-19 era

作　　者：焦国慧 陈静瑜 Jiao Guohui;Chen Jingyu(Wuxi People's Hospital Affiliated to Nanjing Medical University,Wuxi Lung Transplant Center,Jiangsu Lung Transplant Center,Wuxi 214000,China)

机构地区：[1]南京医科大学附属无锡人民医院无锡市器官移植研究院江苏省肺移植中心,江苏无锡214000

出　　处：《器官移植》2021年第5期506-511,共6页Organ Transplantation

基　　金：国家自然科学基金面上项目(82070059);无锡市新型冠状病毒感染应急防治科技专项项目(N2020X002)。

摘　　要：肺移植技术在全球经历了近半个世纪的发展,在中国也高速发展了二十余年,中国肺移植逐渐融入国际肺移植大家庭。2020年新型冠状病毒肺炎(新冠肺炎)疫情暴发,既是对中国肺移植发展的挑战,也使得全球同行关注中国肺移植发展,加速了国际间的交流与合作。随着对新冠肺炎重症患者肺移植的临床和基础研究逐步深入,移植科医师对于未来中国肺移植在供者的维护、高龄和儿童受者的选择、围手术期管理等方面有了更多的认知和思考。对于肺移植相关学科交叉领域的研究,需要开展设计优良、多方协作的临床试验,不断推进学科理论和实践的创新。Lung transplantation has been advanced for nearly half a century around the globe,and it has been developed rapidly for over 20 years in China.The field of lung transplantation in China has been gradually integrated into the international community.The outbreak of novel coronavirus pneumonia(COVID-19)in 2020 brought big challenges,as well as diverted the worldwide attention to the development of lung transplantation in China,accelerating international communication and cooperation.With the steadily deepening of clinical and basic research on lung transplantation for severe cases of COVID-19,organ transplant physicians have deepened the understanding and thinking of the maintenance of donors,selection of elderly and pediatric candidates,and perioperative management of recipients,as the future perspective of lung transplantation in China.For interdisciplinary research related to lung transplantation,it is necessary to carry out multi-center clinical trials with qualified study design and constantly promote the theoretic and practical innovation.

关 键 词：肺移植 新型冠状病毒肺炎(COVID-19) 急性呼吸窘迫综合征(ARDS) 体外膜肺氧合(ECMO) 离体肺灌注技术(EVLP) 肺源分配评分(LAS) 器官分配 

分 类 号：R617[医药卫生—外科学] R563[医药卫生—临床医学]