肺移植术后排斥反应的影像学检查方法现状及展望  

Current status and prospect of imaging examination methods for rejection after lung transplantation

作　　者：徐琳 严浩吉 王俊杰 唐宏涛 李偲涵 陈婷婷 张涵 付思怡 田东[1,2] Xu Lin;Yan Haoji;Wang Junjie;Tang Hongtao;Li Caihan;Chen Tingting;Zhang Han;Fu Siyi;Tian Dong(Heart and Lung Transplant Research Laborary,Affiliated Hospital of North Sichuan Medical College,Nanchong 637000,China;不详)

机构地区：[1]川北医学院附属医院心肺移植研究室,四川南充637000 [2]川北医学院附属医院院士(专家)工作站

出　　处：《器官移植》2021年第5期544-549,共6页Organ Transplantation

基　　金：医学影像四川省重点实验室开放课题(MIKLSP202007);南充市市校合作科研专项(19SXHZ0189);川北医学院附属医院科研发展计划项目(2021ZK003)。

摘　　要：肺移植是治疗终末期肺病的唯一有效手段,其术后发生的排斥反应是影响受者预后的主要因素。影像学检查可作为无创手段,辅助其他检查监测肺移植术后排斥反应。目前已报道的影像学方式较多,明确各种影像学检查的优势与不足,有助于排斥反应的早期诊断,使得肺移植受者可以得到及时治疗,进而提高其生活质量及预后。本文对肺移植术后排斥反应各种影像学检查的利弊及进展进行综述,为寻找肺移植术后排斥反应的最佳无创检查手段提供参考,提高受者远期生存。Lung transplantation is the only effective therapeutic option for end-stage lung diseases,and postoperative rejection is the main factor affecting clinical prognosis of the recipients.Imaging examination can be utilized as a noninvasive tool to assist other examinations in monitoring rejection after lung transplantation.At present,multiple imaging examination methods have been reported.The advantages and disadvantages of various imaging examinations have been clarified,which may promote early diagnosis of rejection,deliver timely treatment for lung transplant recipients and improve the quality of life and clinical prognosis.In this article,the advantages,disadvantages and research progress upon different imaging examinations for rejection after lung transplantation were reviewed,aiming to provide reference for identifying the optimal noninvasive examination approach for rejection after lung transplantation and enhance the longterm survival of the recipients.

关 键 词：肺移植 急性排斥反应 慢性移植肺功能障碍 胸部X线检查 CT MRI 正电子发射计算机体层显像仪(PET/CT) 超声检查 

分 类 号：R617[医药卫生—外科学] R445[医药卫生—临床医学]