A new semi-quantitative Surface-Enhanced Raman Spectroscopy (SERS) method for detection of maleimide (2,5-pyrroledione) with potential application to astrobiology  

作　　者：J.Aramendia L.Gomez-Nubla M.L.Tuite K.H.Williford K.Castro J.M.Madariaga 

机构地区：[1]Jet Propulsion Laboratory,California Institute of Technology,4800 Oak Grove Dr,Pasadena,CA 91109,United States [2]Department of Analytical Chemistry,University of the Basque Country UPV/EHU,P.O.Box 644,48080 Bilbao,Spain

出　　处：《Geoscience Frontiers》2021年第5期421-426,共6页地学前缘（英文版）

基　　金：supported through the“Terrestrial and Planetary Alteration Processes”strategic project(ref.PES 18/57);funded by the University of the Basque Country(UPV/EHU).

摘　　要：Nitrogen-containing heterocyclic compounds are fundamental biochemical components of all life on Earth and,presumably,life elsewhere in our solar system.Detection and characterization of these compounds by traditional solvent extraction,chromatographic separation,and GC-MS analysis require more sample mass than will be available from samples returned to Earth from Mars.With its small sample mass requirement,Surface Enhanced Raman Spectroscopy could be an appropriate technique for analysis of returned samples.We have developed a SERS method for the detection of maleimide(2,5-pyrroledione),an N-containing heterocycle with a structure that is widespread in biochemicals.This semi-quantitative methodology accurately determines maleimide concentration in the range from 60 mg/mL to 120 mg/mL.We present a maleimide SERS standard spectrum which will be useful as a reference for future works.The present work demonstrates an easy,accurate,and effective method for the non-destructive qualitative and semi-quantitative study of maleimide as a first step toward developing a method for analysis of related compounds.

关 键 词：MALEIMIDE Surface-Enhanced Raman Spectroscopy ASTROBIOLOGY BIOSIGNATURE Extraterrestrial life 

分 类 号：Q693[生物学—生物物理学]