临床药师参与1例肺癌患者伴有乙型肝炎表面抗原阳性患者抗病毒治疗的药学实践  

Clinical Pharmacists Participating in Pharmaceutical Practice of Antiviral Medication in Lung Cancer Patients with HBsAg Positive

作　　者：龚银华 张小刚[2] 马雅斌 GONG Yin-hua;ZHANG Xiao-Gang;MA Ya-Bin(Department of Pharmacy,The First Affiliated Hospital of Soochow University,Suzhou Jiangsu 215500,China;Department of Pharmacy,Shanghai East Hospital Affiliated to Tongji University,Shanghai 200120,China)

机构地区：[1]苏州大学附属第一医院,江苏苏州215000 [2]同济大学附属东方医院,上海200000

出　　处：《抗感染药学》2021年第6期898-901,共4页Anti-infection Pharmacy

摘　　要：目的:探究临床药师参与乙型肝炎表面抗原(HBsAg)阳性的肺癌患者围化疗期抗病毒治疗策略的药学实践过程,为此类患者临床安全、合理用药提供参考。方法:临床药师参与会诊,并结合患者实际病例特征(肝功能、二对半定量、HBV-DNA载量等)和相关指南及文献,协助临床制订个体化用药方案和必要的抗病毒治疗策略。结果:临床药师参与临床治疗后,规范使用恩替卡韦抗病毒治疗并实施全过程的药学监护,肝功能等指标较为稳定,有效促进了肺癌患者后续化疗的顺利开展。结论:临床药师参与临床肿瘤患者治疗团队并开展药学监护,提高了临床治疗用药的合理性,减少不良事件的发生,发挥积极作用。Objective:To explore the pharmaceutical practice process of clinical pharmacists involved in antiviral medication strategies for lung cancer patients with hepatitis B surface antigen(HBsAg)positive during perichemothera-py,and to provide reference in the clinical safety and rational drug use for such patients.Methods:Clinical pharmacists participated in the consultation,and assisted the clinical formulation of individualized drug regimen and necessary antiviral medication strategy by combining the actual patient characteristics(liver function,two-half quantification,HBV-DNA load,etc.)and relevant guidelines and literatures.Results:After the participation of clinical pharmacists in clini-cal medication,the standard usage of entecavir antiviral therapy and the implementation of the whole process of pharmaceutical care,liver function and other indicators were relatively stable,effectively promoting the smooth development of follow-up chemotherapy for lung cancer patients.Conclusion:Clinical pharmacists participated in the treatment team of clinical tumor patients and carried out pharmaceutical care,which improved the rationality of clinical medication,reduced the occurrence of adverse events,and played a positive role.

关 键 词：乙型肝炎表面抗原 肺癌 化疗方案 药学服务 

分 类 号：R969[医药卫生—药理学]