微创埋线联合扶正祛瘀化痰方对慢性阻塞性肺疾病稳定期肺肾气虚兼血瘀型患者肺功能和生活质量的影响  

Effects of micro-invasion catgut embedding therapy combined with Fuzheng Qvyu Huatan formula on pulmonary function and the quality-of-life of patients with stable COPD of lung-kidney qi deficiency and blood stasis

作　　者：王虹 王余民 WANG Hong;WANG Yumin(Department of TCM,Shanghai Fifth People's Hospital,Fudan University,Shanghai 200240)

机构地区：[1]复旦大学附属上海市第五人民医院中医科,上海200240

出　　处：《河北中医》2021年第4期648-652,共5页Hebei Journal of Traditional Chinese Medicine

基　　金：上海市闵行区自然科学研究课题(编号:2018MHZ013)

摘　　要：目的观察微创埋线联合扶正祛瘀化痰方对慢性阻塞性肺疾病(COPD)稳定期肺肾气虚兼血瘀型患者肺功能和生活质量的影响。方法将93例COPD稳定期肺肾气虚兼血瘀型患者按照随机数字表法分为2组,对照组47例予西医常规治疗联合扶正祛瘀化痰方口服治疗,治疗组46例在对照组治疗基础上联合微创埋线治疗。2组疗程均为3个月。观察2组治疗前后肺功能指标第1 s用力呼气容积占预计值百分比(FEV_(1)%pred)、最大呼气流量占预计值百分比(PEF%pred)、FEV_(1)/FVC变化,比较2组治疗前后中医证候评分、COPD患者自我评估测试(CAT)评分、圣乔治呼吸问卷(SGRQ)评分、莱斯特咳嗽问卷(LCQ)评分变化。结果2组治疗后FEV_(1)%pred、FEV_(1)/FVC、PEF%pred均较本组治疗前升高(P<0.05);治疗组治疗后PEF%pred高于对照组(P<0.05)。2组治疗后中医证候咳嗽、咯白痰、喘息、气短、乏力、腰膝痠软、胸闷、唇甲发绀评分及总评分均较本组治疗前降低(P<0.05),且治疗组治疗后咳嗽、喘息、气短、乏力、腰膝痠软、胸闷评分及总评分均低于对照组(P<0.05)。2组治疗后CAT咳嗽、咯痰、胸闷、爬楼气喘、日常活动、外出影响、睡眠、精力评分及总评分均较本组治疗前降低(P<0.05),且治疗组治疗后咳嗽、胸闷、爬楼气喘、日常活动、外出影响、精力评分及总评分均低于对照组(P<0.05)。2组治疗后SGRQ呼吸症状、活动受限、疾病影响评分及总评分均较本组治疗前降低(P<0.05),且治疗组降低更明显(P<0.05)。2组治疗后LCQ生理领域、心理领域、社会领域评分及总评分均较本组治疗前升高(P<0.05),且治疗组升高更明显(P<0.05)。结论在西医常规治疗基础上,应用微创埋线联合扶正祛瘀化痰方治疗COPD稳定期肺肾气虚兼血瘀型,可改善患者临床症状和肺功能,提高生活质量。Objective To observe the effect of micro-invasion catgut embedding therapy combined with Fuzheng Qvyu Huatan formula on pulmonary function and the quality-of-life of patients with stable chronic obstructive pulmonary disease(COPD) of lung-kidney qi deficiency and blood stasis.Methods Totally 93 patients with stable COPD of lung-kidney qi deficiency and blood stasis were randomly divided into control group and treatment group.47 patients in control group were treated with conventional western medicine and Fuzheng Qvyu Huatan formula;46 patients in treatment group were treated with micro-invasion catgut embedding therapy on the basis of control group.Treatmented for 3 months,aiming to compare lung function index(FEV1% pred、PEF% pred,FEV1/FVC),Traditional Chinese Medicine(TCM) syndrome score,COPD assessment test(CAT) score,St George’s Respiratory questionnaire(SGRQ) score and Leicester Cough Questionnaire(LCQ) score.Results Compared with before treatment,FEV1% pred,PEF% pred,and FEV1/FVC were increased in groups after treatment(P <0.05),and PEF% pred was higher in treatment group than in control group(P < 0.05).The TCM syndrome scores(Cough,expectoration,wheezing,shortness of breath,fatigue,sore waist and knees,chest tightness,cyanosis of lips and nails) were decreased in groups after treatment(P < 0.05),of which,most symptoms scores except for expectoration,cyanosis of lips and nails were lower in treatment group than in the control group(P < 0.05),CAT score(Cough,expectoration,chest tightness,climbing asthma,daily activities,outgoing influence,sleep,energy) were decreased in groups after treatment(P < 0.05),of which,most symptoms except for expectoration and sleep were lower in treatment group than in control group(P < 0.05).SGRQ score(respiratory symptoms,limited activity,disease impact)were lower than this group before treatment(P < 0.05),and the decrease in the treatment group was more obvious(P < 0.05),and LCQ score(Physiological,psychological and social fields) were higher than this group before treatment

关 键 词：肺疾病 慢性阻塞性 中西医结合疗法 埋线 

分 类 号：R563.058[医药卫生—呼吸系统] R245.91[医药卫生—内科学]