伴胃肠结构畸形的原发性免疫缺陷病  

Primary immunodeficiency with malformation of gastrointestinal structure

作　　者：谷雨 孙金峤 GU Yu;SUN Jin-qiao(Department of Clinical Immunology,Children’s Hospital of Fudan University,Shanghai 201102,China)

机构地区：[1]复旦大学附属儿科医院临床免疫科,上海201102

出　　处：《中国实用儿科杂志》2021年第7期494-497,共4页Chinese Journal of Practical Pediatrics

摘　　要：原发性免疫缺陷病(PID)是一类由于基因突变导致免疫功能受损的疾病,最常见的临床表现为反复、严重感染。随着对PID认识的不断深入,越来越多的PID病种被识别,其中有部分PID除免疫功能受损外,还伴有胃肠结构畸形。为更好地认识这部分疾病,文章对近年发现的伴胃肠结构畸形的PID作一阐述。Primary immunodeficiency disease(PID)is a type of disease in which immune function is impaired due to genetic mutations.The most common clinical manifestation is repeated and severe infections.With the deepening of the understanding of PID,more and more types of PID diseases have been identified,and some of them are accompanied by gastrointestinal structural abnormalities in addition to impaired immune function.In order to understand this part of the disease better,this article reviews the PID with gastrointestinal structural abnormalities discovered in recent years.

关 键 词：原发性免疫缺陷病 胃肠道 结构畸形 

分 类 号：R72[医药卫生—儿科]