多种铁剂治疗小儿缺铁性贫血的临床研究  

Clinical Study on Treatment of Iron Deficiency Anemia in Children with Various Iron Agents

作　　者：钟翠玲 ZHONG Cuiling(Hunnan District Hospital of Shenyang City,Shenyang 110168,China)

机构地区：[1]辽宁省沈阳市浑南区医院,辽宁沈阳110168

出　　处：《中国医药指南》2021年第24期51-52,共2页Guide of China Medicine

摘　　要：目的关于右旋糖酐铁和葡萄糖酸亚铁对小儿缺铁性贫血进行治疗的效果比较。方法选择到我院门诊治疗的56例小儿缺铁性贫血患儿作为研究对象,时间为2018年1月至2019年3月,随机分为观察组和对照组,每组28例,观察组患儿均选择采用右旋糖酐铁进行间断口服治疗,对照组患儿则选择葡萄糖酸亚铁进行治疗,比较两组患儿经过不同治疗以后的临床效果。结果观察组治疗总有效率为100.00%(28/28),对照组治疗总有效率为67.86%(19/28),观察组不良反应发生率为3.57%(1/28),对照组为32.14%(9/28),P<0.05,存在统计学差异性;比较两组患者治疗以后的血红蛋白、血清铁和网织红细胞等相关指标,观察组明显优于对照组,P<0.05,存在统计学差异性。结论对小儿缺铁性贫血在进行治疗的时候通过左旋糖苷铁进行间断口服治疗所取得的效果优于选择葡萄糖酸亚铁治疗的效果,可以提高治疗的总有效率,降低不良反应的发生率,改善患儿的相关实验室指标,值得推广。Objective To compare the effects of iron dextran and ferrous gluconate on iron deficiency anemia in children.Methods The 56 children with iron-deficiency anemia who were treated in the outpatient clinic of our hospital were selected as the research objects,and the period was from January 2018 to March 2019.They were randomly divided into observation group and control group,28 cases in each group,children in observation group chose to use iron dextran for intermittent oral treatment,and the control group chose ferrous gluconate for treatment.The clinical effects of the two groups of children after different treatments were compared.Results The total effective rate of the observation group was 100.00%(28/28),the total effective rate of the control group was 67.86%(19/28),the incidence of adverse reactions in the observation group was 3.57%(1/28),and the control group was 32.14%(9/28),P<0.05,there were statistical differences.The hemoglobin,serum iron and reticulocytes after treatment were compared between the two groups,the observation group was significantly better than the control group,P<0.05,there were statistics difference.Conclusion The effect of intermittent oral treatment with iron dextran in the treatment of iron deficiency anemia in children is better than that of ferrous gluconate treatment,which can improve the total effective rate of treatment and reduce the incidence of adverse reactions.To improve the relevant laboratory indicators of children,it is worth promoting.

关 键 词：铁剂 小儿缺铁性贫血 治疗效果 

分 类 号：R556.3[医药卫生—血液循环系统疾病]