胶艾护胎汤联合黄体酮注射液治疗先兆流产伴绒毛膜下血肿临床研究  

Clinical Study on Jiao’ai Hutai Tang Combined with Progesterone Injection for Threatened Abortion Complicated with Subchorionic Hematoma

作　　者：朱新全 李辉杰 袁渭清 ZHU Xinquan;LI Huijie;YUAN Weiqing(Department of reproductive medicine,Minquan Hospital of traditional Chinese medicine,Henan Minquan 476800;Department of reproductive medicine,Shangqiu Fifth People's Hospital,Shangqiu 476000,Henan)

机构地区：[1]民权县中医院生殖医学科,河南民权476800 [2]商丘市第五人民医院生殖医学科,河南商丘476000

出　　处：《新中医》2021年第16期77-80,共4页New Chinese Medicine

摘　　要：目的:观察胶艾护胎汤联合黄体酮注射液治疗先兆流产伴绒毛膜下血肿患者的临床疗效及其对血清孕酮(P)、人绒毛膜促性腺激素(HCG)含量,以及母婴结局的影响。方法:选取90例先兆流产伴绒毛膜下血肿患者为研究对象。按照随机数字表法分为2组各45例。对照组采用黄体酮治疗,观察组在对照组治疗方案的基础上合用胶艾护胎汤治疗。观察治疗后临床疗效及母婴结局,比较2组治疗前后血清HCG及P含量;观察2组治疗后绒毛膜下血肿面积、阴道流血时间及血肿消失时间。结果:临床疗效总有效率观察组93.33%,高于对照组77.78%,2组总有效率比较,差异有统计学意义(P<0.05)。治疗后,2组血清P、HCG含量均升高,且观察组高于对照组,差异有统计学意义(P<0.05)。观察组绒毛膜下血肿面积小于对照组,阴道流血时间及血肿消失时间均短于对照组,差异均有统计学意义(P<0.05)。观察组足月妊娠率高于对照组,流产发生率低于对照组,差异均有统计学意义(P<0.05)。结论:胶艾护胎汤联合黄体酮注射液治疗先兆流产伴绒毛膜下血肿临床疗效良好,可缩短血肿消退及阴道流血时间,缩小血肿,改善母婴结局,其机制可能与调节血清HCG及P含量有关。Objective:To observe the clinical effect of Jiao’ai Hutai tang combined with progesterone injection for patients with threatened abortion complicated with subchorionic hematoma,and its effect on the contents of progesterone(P) and human chorionic gonadotropin(HCG) in serum,and maternal-infant outcome. Methods:A total of 90 cases of patients with threatened abortion complicated with subchorionic hematoma were selected as the study objects,and were divided into two groups according to the random number table method,45 cases in each group. The control group was given progesterone,and the observation group was additionally given Jiao’ai Hutai tang based on the treatment of the control group. After treatment,the clinical effect and maternal-infant outcome were observed. Before and after treatment,contents of HCG and P in serum were compared between the two groups. After treatment,the size of subchorionic hematoma,vaginal bleeding duration,and the disappearance time of hematoma were observed in the two groups. Results:The total clinical effective rate was 93.33% in the observation group,higher than that of 77.78% in the control group,the difference being significant(P<0.05). After treatment, contents of HCG and P in serum in the two groups were increased, and the contents in the observation group were higher than those in the control group, the difference being significant(P<0.05). The size of subchorionic hematoma in the observation group was smaller than that in the control group, vaginal bleeding duration shorter, and the disappearance time of hematoma earlier, differences being significant(P<0.05). The rate of full-term pregnancy in the observation group was higher than that in the control group, and the incidence of abortion was lower,differences being significant(P<0.05). Conclusion: In the treatment of threatened abortion complicated with subchorionic hematoma,the therapy of Jiao’ai Hutai tang combined with progesterone injection has a good clinical effect. It can shorten vaginal bleeding duration and regr

关 键 词：先兆流产伴绒毛膜下血肿 黄体酮注射液 胶艾护胎汤 孕酮 人绒毛膜促性腺激素 足月妊娠 阴道流血时间 血肿消失时间 

分 类 号：R714.21[医药卫生—妇产科学]