奥美拉唑肠溶胶囊致速发型过敏反应  

Immediate-type hypersensitivity induced by omeprazole enteric coated capsules

作　　者：冯波[1] 刘鹏 张亚军 胡鹏[4] Feng Bo;Liu Peng;Zhang Yajun;Hu Peng(Department of Neurology,Binzhou Medical University Hospital,Shandong Province,Binzhou 256603,China;Department of Neurosurgery,Boxing County Hospital of Traditional Chinese Medicine,Shandong Province,Boxing 256500,China;Department of Internal Medicine,Traditional Chinese Medicine Hospital of Fengjie County,Chongqing 404699,China;Department of Spinal Surgery,Binzhou Medical University Hospital,Shandong Province,Binzhou 256603,China)

机构地区：[1]滨州医学院附属医院神经内科,滨州256603 [2]山东省博兴县中医院神经外科,博兴256500 [3]重庆市奉节县中医院内科,重庆404699 [4]滨州医学院附属医院脊柱外科,滨州256603

出　　处：《药物不良反应杂志》2021年第8期443-444,共2页Adverse Drug Reactions Journal

基　　金：山东省中医药科技发展计划(2019‑0502)。

摘　　要：1例39岁女性因胃脘部疼痛口服奥美拉唑肠溶胶囊40 mg。服药约2.5 h后出现全身瘙痒,继之全身出现荨麻疹样皮疹,伴呼吸困难、心悸。考虑为奥美拉唑肠溶胶囊引起的过敏反应,立即给予地塞米松、葡萄糖酸钙和维生素C等抗过敏药物治疗,2 h后呼吸困难、心悸、瘙痒症状缓解,3.5 h后皮疹完全消退。A 39-year-old female patient took omeprazole enteric-coated capsules 40 mg orally for stomachache.About 2.5 hours after the medication,the patient developed generalized itching,followed by urticaria like rash all over the body,dyspnea,and palpitations.Anaphylaxis due to omeprazole enteric coated capsules was considered.Anti-allergic drugs such as dexamethasone,calcium gluconate,and vitamin C were given immediately.Two hours later,dyspnea,palpitations,and pruritus were relieved and the rash completely subsided 3.5-hours later.

关 键 词：奥美拉唑 给药 口服 过敏反应 

分 类 号：R969.3[医药卫生—药理学]