Crosstalk in polymer microelectrode arrays  

作　　者：Yi Qiang Wen Gu Zehua Liu Shanchuan Liang Jae Hyeon Ryu Kyung Jin Seo Wentai Liu Hui Fang 

机构地区：[1]Department of Electrical and Computer Engineering,Northeastern University,Boston,MA 02115,USA [2]Department of Bioengineering,University of California,Los Angeles,Los Angeles,CA 90095,USA [3]Department of Bioengineering,Northeastern University,Boston,MA 02115,USA

出　　处：《Nano Research》2021年第9期3240-3247,共8页纳米研究（英文版）

基　　金：supported by National Science Foundation award 1847215,National Institute of Neurological Disorders and Stroke award 1RFINS 118301-01 and Samsung Global Research Outreach Award.

摘　　要：Thin-film polymer microelectrcxje arrays(MEAs)facilitate the high-resolution neural recording with its superior mechanical compliance.However,the densely packed electrodes and interconnects along with the ultra-thin polymeric encapsulation/substrate layers give rise to non-negligible crosstalk,which could result in severe interference in the neural signal recording.Due to the lack of standardized characterization or modeling of crosstalk in neural electrode arrays,to date,crosstalk in polymer MEAs remains poorly understood.In this work,the crosstalk between two adjacent polymer microelectrodes is measured experimentally and modeled using equivalent circuits.Importantly,this study demonstrated a two-well measuring platform and systematically characterized the crosstalk in polymer microelectrodes with true isolation of the victim channel and precise control of its grounding condition.A simple,unified equation from detailed circuit modeling was proposed to calculate the crosstalk in different environments.Finite element analysis(FEA)analysis was conducted further to explore the crosstalk in more aggressively scaled polymer electrode threads.In addition to standardizing neural electrode array crosstalk characterization,this study not only reveals the dependence of the crosstalk in polymer MEAs on a variety of key device parameters but also provides general guidelines for the design of thin polymer MEAs for high-quality neural signal recording.

关 键 词：crosstalk effect flexible microelectrodes equivalent circuit modelling finite element analysis POLYMER 

分 类 号：O63[理学—高分子化学]