β-磷酸三钙骨免疫学特性的研究进展  

Research Progress on Osteoimmunology Properties ofβ-TCP

作　　者：单宇华 陈振琦[1] SHAN Yuhua;CHEN Zhenqi(Department of Orthodontics, Shanghai Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine, National Clinical Research Center for Oral Disease, Shanghai Key Laboratory of Stomatology & Shanghai Research Institute of Stomatology, Shanghai 200011, China)

机构地区：[1]上海交通大学医学院附属第九人民医院·口腔医学院口腔正畸科,国家口腔疾病临床医学研究中心,上海市口腔医学重点实验室,上海市口腔医学研究所,上海200011

出　　处：《口腔医学研究》2021年第9期787-790,共4页Journal of Oral Science Research

摘　　要：β-磷酸三钙(β-TCP)作为植骨材料具有优良的生物相容性和骨传导性,免疫反应在决定β-TCP体内转归中起着重要的作用,β-TCP作为异物被免疫系统识别,触发免疫细胞的不同行为模式,从而影响着新骨形成。了解β-TCP植入后诱导的免疫环境和成骨之间的影响,有助于诱导最佳的局部免疫环境,为最终骨整合提供成骨和破骨的最佳平衡,本文将对β-TCP在骨免疫学领域的研究作一综述。β-tricalcium phosphate(β-TCP),as bone graft material,has excellent biocompatibility and osteoconductivity.Immune response plays an important role in determining the internal outcome ofβ-TCP.β-TCP,as a foreign body,is recognized by the immune system and triggers different behavior patterns of immune cells,thus affecting the formation of new bone.It is helpful to understand the influence of immune environment and osteogenesis induced byβ-TCP.In order to explore the optimal immune environment that provides balance between osteogenesis and osteoclastogenesis for osseointegration,this paper reviews the research ofβ-TCP in the field of bone immunology.

关 键 词：Β-磷酸三钙 骨免疫学 骨替代物 骨再生 

分 类 号：TP3[自动化与计算机技术—计算机科学与技术]