2020年至2021年南通地区泌尿生殖道支原体感染情况分析  

An Analysis of Urogenital Tract Mycoplasma Infectionin Nantong Area During 2020-2021

作　　者：徐鑫鑫[1] 蔡花[1] 彭静静 褚福营[2] XU Xinxin;CAI Hua;PENG Jingjing;CHU Fuying(Department of Laboratory Medicine,Affiliated Hospital of Nantong University,Nantong 226000,China;Department of Laboratory Medicine,Nantong First People’s Hospital,Nantong 226000,China)

机构地区：[1]南通大学附属医院检验科,江苏南通226000 [2]南通市第一人民医院检验科,江苏南通226000

出　　处：《标记免疫分析与临床》2021年第8期1356-1360,共5页Labeled Immunoassays and Clinical Medicine

基　　金：南通市科技项目(编号:JC2020070)。

摘　　要：目的探讨2020年至2021年南通地区泌尿生殖道支原体感染情况,为临床提供参考。方法使用支原体培养试剂盒对我院2020年1月至2021年4月就诊的2 123例泌尿生殖道感染患者标本进行支原体培养。结果 2 123例泌尿生殖道标本中共检出支原体阳性标本718例,感染率为33.82%,其中单纯解脲脲原体(Uu)感染637例(30.00%),单纯人型支原体(Mh)感染21例(0.99%),Uu+Mh混合感染60例(2.83%)。Uu感染率明显高于Mh和Uu+Mh感染率。2 123例就诊者中女性1 133例,男性990例。Uu、Mh、Uu+Mh在女性中感染率分别为50.75%(575/1 133)、0.71%(8/1 133)、5.83%(66/1 133),且在20~30岁年龄段Uu感染率(59.17%)较高;在男性中感染率分别为29.80%(295/990)、1.31%(13/990)、4.04%(40/990),且在20~30岁年龄段Uu感染率(34.23%)最高。女性泌尿生殖道疾病中女性不孕症Uu感染率(61.11%)最高,其次为宫颈炎性疾病、阴道炎、尿道炎;男性泌尿生殖道疾病中男性不育症Uu感染率(39.13%)最高,其次为尿道炎、前列腺炎、龟头炎。阴道炎患者阴道清洁度Ⅰ~Ⅱ度中,Uu感染率为40.88%(56/137),Ⅲ~Ⅳ度中Uu感染率为68.50%(87/127),差异具有统计学意义(P<0.05)。且Uu阳性患者治疗后感染率下降,阴道清洁度等级也降低。女性不孕症Uu阳性患者中抗精子抗体阳性率为10.57%(24/227),Uu阴性患者中抗精子抗体阳性率为2.40%(3/125),差异具有统计学意义(P<0.05)。结论南通地区检出的支原体感染以Uu为主,在不同性别、不同年龄人群及不同疾病中分布有所差异,且阴道炎患者阴道越不清洁,Uu感染率越大;女性不孕症患者Uu感染率越大,抗精子抗体阳性率越高。这可为临床上相关疾病的防治提供参考。Objective To analysis the urogenital tract mycoplasma infection in Nantong area during 2020-2021, and to provide the reference for clinical practice.Methods The culture kit was used to detect 2 123 samples suspected of urogenital tract infection in our hospital from January, 2020 to April, 2021.Results In the 2 123 patients submitted for examination, the number of positive cases was 718, with the positive rate 33.82%, among which 637 cases(30.00%) were Uu-positive, 21 cases(0.99%) were Mh-positive, and 60 cases(2.83%) were mixed infection of Uu and Mh. The Uu infection levels were higher than Mh and mixed infection levels. Among the 2 123 patients, 1 133 cases were female, and 990 cases were male. Among female cases, the infection rate of only Uu was 50.75%(575/1133), the infection rate of only Mh was 0.71%(8/1133), and the infection rate of Uu and Mh was 5.83%(66/1133). And we observed a higher rate of infection(59.17%) among people whose age were between 20 to 30 years old. In male, the infection rate of only Uu was 29.80%(295/990), the infection rate of only Mh was 1.31%(13/990), and the infection rate of Uu and Mh was 4.04%(40/990). And the highest rate of infection(34.23%) in the man was observed among people whose age were from 20 to 30 years old. In female, the highest rate of Uu infection(61.11%) in urogenital tract diseases was female infertility, and followed with cervicitis, vaginitis and urethritis. In male, the highest rate of Uu infection(39.13%) in urogenital tract diseases was male infertility, and followed with urethritis, prostatitis and balanitis. The infection rate of Uu in vaginitis patients with Ⅰ-Ⅱ vaginal cleanliness was 40.88%(56/137), and in Ⅲ-Ⅳ vaginal cleanliness was 68.50%(87/127), with a significant difference(P<0.05). The infection rate was decreased in Uu-positive patients after treatment, and the grade of vaginal cleanliness was also decreased. The positive rate of AsAb in Uu-positive patients with female infertility was 10.57%(24/227), while the negative rate of AsAb was

关 键 词：支原体 解脲脲原体 人型支原体 感染率 

分 类 号：R3753[医药卫生—病原生物学]