MRI IDEAL-IQ序列对骨质疏松症的诊断价值  

Diagnostic value of MRI IDEAL-IQ sequence in patients with osteoporosis

作　　者：高萌[1] 张健[1] 蒋翠花[1] 金乔梅 张东建[1] 孙胜禄[2] GAO Meng;ZHANG Jian;JIANG Cuihua;JIN Qiaomei;ZHANG Dongjian;SUN Shenglu(Department of Radiology,Jiangsu Province Academy of Traditional Chinese Medicine,Nanjing 210028,China.)

机构地区：[1]江苏省中医药研究院转化医学实验室,江苏南京210028 [2]江苏省中医药研究院放射科,江苏南京210028

出　　处：《中国中西医结合影像学杂志》2021年第5期478-480,共3页Chinese Imaging Journal of Integrated Traditional and Western Medicine

基　　金：国家自然科学基金(82003989,21907053)。

摘　　要：目的:探讨MRI多点非对称回波采集与迭代最小二乘法水脂分离-智能定量技术(IDEAL-IQ)对骨质疏松症(OP)的诊断价值。方法:收集同时行腰椎定量CT(QCT)及IDEAL-IQ序列检查的患者39例,分别采用QCT检测骨密度和IDEAL-IQ序列检测椎体内骨髓脂肪分数(FF)。根据所测骨密度将其分为骨量正常组、低骨量组和OP组。比较3组间腰椎椎体FF值及年龄差异,分析FF值与骨密度的相关性,以及FF值对OP的诊断效能。结果:OP组年龄显著高于骨量正常组和低骨量组,差异有统计学意义(P<0.05)。3组FF值比较差异有统计学意义(P<0.05),且OP组FF值均高于另2组(均P<0.05);FF值与年龄呈正相关(r=0.559);FF值与骨密度呈负相关(r=-0.67);采用FF值评价OP的ROC曲线显示,AUC为0.899,诊断敏感度为0.875,特异度为0.839。结论:IDEAL-IQ测量的椎体FF值对OP具有诊断价值。Objective:To explore the value of IDEAL-IQ in evaluation of osteoporosis. Methods:A total of 39 patients were examined by quantitative CT (QCT) and IDEAL-IQ. QCT was used to measure lumber bone density and IDEAL-IQ sequence was scanned to measure the fat fraction (FF) value of vertebral bone marrow,respectively. According to the measured bone density,39 patients were divided into 3 groups:normal bone mass group,low bone mass group and osteoporosis group. One-way analysis of variance was applied to compare the differences of FF value and age among the three groups. Pearson correlation analysis was applied to analyze the correlation between FF value and bone density. ROC curve was used to analyze the diagnostic efficacy of FF value for osteoporosis. Results:The age of osteoporosis group was significantly older than that of the other two groups (P<0.05). FF value of the three groups had statistically difference (P<0.05),while that of osteoporosis group was the highest (both P<0.05),and FF value was positively correlated with age (r=0.559) and negatively correlated with bone density (r=-0.67). The ROC curve analysis in evaluating osteoporosis by FF value showed that AUC was 0.899,the sensitivity was 0.875,and the specificity was 0.839. Conclusion:IDEAL-IQ is valuable for the diagnosis of osteoporosis.

关 键 词：磁共振成像 骨质疏松 骨密度 诊断 

分 类 号：R580[医药卫生—内分泌]