催产素引产时间对妊娠晚期羊水过少患者妊娠结局的影响  

The Effect of Oxytocin Induction Time on the Pregnancy Outcome of Oligohydramnios in the Third Trimester of Pregnancy

作　　者：黄庆桃 陈环 张春华 HUANG Qingtao;CHEN Huan;ZHANG Chunhua(Luoding People’s Hospital,Luoding 527200,China;不详)

机构地区：[1]罗定市人民医院,广东罗定527200

出　　处：《中外医学研究》2021年第23期76-78,共3页CHINESE AND FOREIGN MEDICAL RESEARCH

基　　金：云浮市医学科学技术研究项目(2019B053)。

摘　　要：目的:探究催产素引产时间对妊娠晚期羊水过少患者妊娠结局的影响。方法:回顾性分析2019年1月-2020年12月于罗定市人民医院产科住院分娩的180例妊娠晚期羊水过少患者。根据累积静脉滴注催产素时间不同,将其分为三组,即A组<10 h,B组10~20 h,C组>20 h,比较三组围产儿不良结局和妊娠不良结局,包括羊水污染、胎儿窘迫、出生后1 min Apgar评分、过期妊娠、胎膜早破、产后出血量、分娩方式及阴道分娩患者的产程。结果:C组羊水污染的发生率、宫内窘迫的发生率、产程、产后出血量及剖宫产的发生率明显高于A组和B组,同时C组胎膜早破的比率高于A组,差异均有统计学意义(P<0.05);三组新生儿出生后1 min Apgar评分<7分的比例和过期妊娠的发生率比较差异无统计学意义(P>0.05)。结论:妊娠晚期羊水过少患者的催产素累计使用时间超过20 h,会增加羊水污染和宫内窘迫等围产儿结局的发生率和产后出血量,胎膜早破等妊娠结局的发生率会明显增高,同时阴道分娩产程延长,增加患者和胎儿的危险性。Objective:To explore the effect of Oxytocin induction time on the pregnancy outcome of patients with oligohydramnios in the third trimester of pregnancy.Method:A retrospective analysis of 180 patients with oligohydramnios in the third trimester of pregnancy who were hospitalized in the Obstetrics Department of Luoding People’s Hospital from January 2019 to December 2020.According to the cumulative time of intravenous infusion of Oxytocin,they were divided into three groups,namely group A<10 hours,group B 10-20 hours,and group C>20 hours.The adverse perinatal outcomes and adverse pregnancy outcomes of the three groups were compared,including amniotic fluid contamination,fetal distress,Apgar score at 1 minute after birth,prolonged pregnancy,premature rupture of membranes,postpartum hemorrhage,delivery methods,and the labor process of patients with vaginal delivery.Result:The incidence of amniotic fluid contamination,intrauterine distress,labor time,postpartum hemorrhage,and the incidence of cesarean section in group C were significantly higher than those of group A and group B.At the same time,the rate of premature rupture of membranes in group C was higher than that of group A,the differences were statistically significant(P<0.05).The proportion of newborns with Apgar score<7 points at 1 minute after birth and the incidence of prolonged pregnancy were not statistically significant between the three groups(P>0.05).Conclusion:The cumulative use of Oxytocin in patients with oligohydramnios in late pregnancy exceeds 20 hours,which will increase the incidence of perinatal outcomes such as amniotic fluid pollution and intrauterine distress,and increase the incidence of pregnancy outcomes such as increased postpartum hemorrhage and premature rupture of membranes.At the same time,the probability of prolonged vaginal delivery has increased,which increases the risk of patients and fetuses.

关 键 词：催产素 羊水过少 引产时间 妊娠结局 

分 类 号：R714.4[医药卫生—妇产科学]