老年结肠癌患者腹腔镜手术中应用七氟醚麻醉的效果  

Effect of sevoflurane anesthesia in laparoscopic surgery for elderly patients with colon cancer

作　　者：段伟琴 DUAN Wei-qin(Department of Anesthesiology,People’s Hospital of Inner Mongolia Autonomous Region,Hohhot 010010,China)

机构地区：[1]内蒙古自治区人民医院手术麻醉科,010010

出　　处：《中国实用医药》2021年第25期11-14,共4页China Practical Medicine

摘　　要：目的分析老年结肠癌患者腹腔镜手术中应用七氟醚麻醉的效果。方法76例老年结肠癌腹腔镜手术患者,按照手术麻醉方法的不同分为对照组和观察组,各38例。对照组患者采用常规麻醉,观察组在对照组的基础上采用七氟醚麻醉。比较两组患者的术后指标、手术前后的肺功能指标[每分钟最大通气量(MVV)、第1秒用力呼气容积(FEV1)、血氧饱和度(SpO2)]、手术前后的心理状态[焦虑自评量表(SAS)、抑郁自评量表(SDS)评分]、不良反应发生情况。结果观察组患者的清醒时间、气管导管拔除时间、住院时间均明显短于对照组,差异有统计学意义(P<0.05)。手术后,观察组患者的MVV(88.26±5.04)L、FEV1(2.81±0.51)L、SpO2(93.13±0.86)%均明显高于对照组的(81.35±4.23)L、(2.27±0.54)L、(90.27±0.92)%,差异有统计学意义(P<0.05)。手术后,观察组患者的SAS评分(34.81±3.75)分、SDS评分(32.46±3.12)分均明显低于对照组的(39.37±3.07)、(40.24±3.35)分,差异有统计学意义(P<0.05)。观察组患者的不良反应发生率2.63%明显低于对照组的18.42%,差异有统计学意义(P<0.05)。结论老年结肠癌腹腔镜手术患者应用七氟醚麻醉的效果显著,安全性高,值得临床推广应用。Objective To analyze the effect of sevoflurane anesthesia in laparoscopic surgery for elderly patients with colon cancer.Methods A total of 76 elderly patients with colon cancer were divided into a control group and an observation group according to different anesthesia methods,with 38 cases in each group.The control group was treated with conventional anesthesia,and the observation group was treated with sevoflurane anesthesia based on the control group.The postoperative indicators,pulmonary function indicators[maximum ventilation volume(MVV),forced expiratory volume in the 1st second(FEV1),blood oxygen saturation(SpO2)]and psychological state[self-rating anxiety scale(SAS)score,self-rating depression scale(SDS)score]before and after surgery,and occurrence of adverse reactions were compared between the two groups.Results The wake-up time,extubation time and hospitalization time of the observation group were obviously shorter than those of the control group,and the difference was statistically significant(P<0.05).After surgery,the MVV(88.26±5.04)L,FEV1(2.81±0.51)L and SpO2(93.13±0.86)%of the observation group were obviously higher than(81.35±4.23)L,(2.27±0.54)L and(90.27±0.92)%of the control group,and the difference was statistically significant(P<0.05).After surgery,the SAS score(34.81±3.75)points and SDS score(32.46±3.12)points of the observation group were obviously lower than(39.37±3.07)and(40.24±3.35)points of the control group,and the difference was statistically significant(P<0.05).The incidence of adverse reactions of the observation group was 2.63%,which was obviously lower than 18.42%of the control group,and the difference was statistically significant(P<0.05).Conclusion Sevoflurane anesthesia has significant effect and high safety for elderly patients with colon cancer,and it is worthy of clinical promotion and application.

关 键 词：老年 结肠癌 七氟醚 腹腔镜手术 肺功能 心理状态 不良反应 

分 类 号：R614[医药卫生—麻醉学] R735.35[医药卫生—外科学]