羟基磷灰石复合及掺杂改性研究进展  

Research Progress of Composite and Doping Modification of Hydroxyapatite Materials

作　　者：田键[1,2,3,4,5] 汤钒 胡攀 朱艳超 古卫乐[1,2,3] 刘旻 徐逸凡 操未青 TIAN Jian;TANG Fan;HU Pan;ZHU Yanchao;GU Weile;LIU Min;XU Yifan;CAO Weiqing(School of Materials Science and Engineering,Hubei University,Wuhan 430062,China;Key Laboratory of Green Preparation and Application of Functional Materials,Ministry of education,Wuhan 430062,China;Application Technology of Green Industrialization of Industrial Waste Hubei Engineering Research Center,Wuhan 430062,China;Yulin Normal University,Research Institute of Calcium Carbonate Industry Development,Yulin 537000,China;Hubei Huda Tianshu New Energy Materials Industry Research and Design Institute Co.,Ltd.,Wuhan 430062,China)

机构地区：[1]湖北大学材料科学与工程学院,湖北武汉430062 [2]功能材料绿色制备与应用教育部重点实验室,湖北武汉430062 [3]工业废弃物绿色产业化应用技术湖北省工程研究中心,湖北武汉430062 [4]玉林师范学院碳酸钙产业发展研究院,广西玉林537000 [5]湖北湖大天沭新能源材料工业研究设计院有限公司,湖北武汉430062

出　　处：《有色金属材料与工程》2021年第4期55-60,共6页Nonferrous Metal Materials and Engineering

基　　金：广西创新驱动发展专项(2018AA21013);湖北大学青年科学基金(201911304000001)。

摘　　要：羟基磷灰石(Hydroxyapatite,HAP)作为生物体骨骼和牙齿的主要无机成分,具有良好的生物相容性和生物活性,因此,被广泛的应用于生物医学领域,尤其是在药物传输和骨组织修复及替代方面。由于HAP本身力学性能较差,且在生物领域扩展应用上有一定的差异性,为了得到综合性能优异的HAP生物材料,HAP复合材料及离子掺杂改性是当今研究的重点。主要综述了HAP的制备方法及其在复合和离子掺杂的研究进展,总结了HAP的优缺点,展望了HAP在生物材料领域的发展前景。Hydroxyapatite(HAP),as the main inorganic component of bone and teeth,shows good biocompatibility and bioactivity,therefore,it is widely used in biomedical field,especially in the aspect of drug delivery and bone tissue repair and replacement.Due to the poor mechanical properties of HAP and the differences in the extended application in the biological field,HAP composite materials and ion doping modification have become the current research focus in order to obtain excellent comprehensive properties of HAP biomaterials.The preparation methods of HAP and the research progress in its composite and ion doping were reviewed,the advantages and disadvantages of HAP materials were summarized,and the development prospect of HAP in the field of biomaterials was prospected.

关 键 词：羟基磷灰石 复合材料 离子掺杂 应用 进展 

分 类 号：TQ126.35[化学工程—无机化工]