Beneficial effects of a decreased meal frequency on nutrient utilization,secretion of luteinizing hormones and ovarian follicular development in gilts  

作　　者：Lun Hua Lianpeng Zhao Zhengyu Mao Wentao Li Jing Li Xuemei Jiang Lianqiang Che Shengyu Xu Yan Lin Zhengfeng Fang Bin Feng De Wu Yong Zhuo 

机构地区：[1]Animal Nutrition Institute,Sichuan Agricultural University,Chengdu 611130,People’s Republic of China [2]Key Laboratory for Animal Disease-Resistant Nutrition of the Ministry of Education of China,Sichuan Agricultural University,Chengdu 611130,People’s Republic of China [3]Key Laboratory of Animal Disease-Resistant Nutrition of Sichuan Province,Sichuan Agricultural University,211 Huimin Road,Wenjiang District,Chengdu 611130,People’s Republic of China

出　　处：《Journal of Animal Science and Biotechnology》2021年第3期1098-1111,共14页畜牧与生物技术杂志（英文版）

基　　金：This study was supported by National Key R&D Program of China(2018YFD0501005);National Natural Science Foundation of China,PR China(31772616).

摘　　要：Background:Replacement gilts are typically fed ad libitum,whereas emerging evidence from human and rodent studies has revealed that time-restricted access to food has health benefits.The objective of this study was to investigate the effect of meal frequency on the metabolic status and ovarian follicular development in gilts.Methods:A total of 36 gilts(Landrace×Yorkshire)with an age of 150±3 d and a body weight of 77.6±3.8 kg were randomly allocated into one of three groups(n=12 in each group),and based on the group allocation,the gilts were fed at a frequency of one meal(T1),two meals(T2),or six meals per day(T6)for 14 consecutive weeks.The effects of the meal frequency on growth preference,nutrient utilization,short-chain fatty acid production by gut microbial,the post-meal dynamics in the metabolic status,reproductive hormone secretions,and ovarian follicular development in the gilts were measured.Results:The gilts in the T1 group presented a higher average daily gain(+48 g/d,P<0.05)and a higher body weight(+4.9 kg,P<0.05)than those in the T6 group.The meal frequency had no effect on the apparent digestibility of dry matter,crude protein,ether extract,ash,and gross energy,with the exception that the T1 gilts exhibited a greater NDF digestibility than the T6 gilts(P<0.05).The nitrogen balance analysis revealed that the T1 gilts presented decreased urine excretion of nitrogen(−8.17 g/d,P<0.05)and higher nitrogen retention(+9.81 g/d,P<0.05),and thus exhibited higher nitrogen utilization than the T6 gilts.The time-course dynamics of glucose,α-amino nitrogen,urea,lactate,and insulin levels in serum revealed that the T1 group exhibited higher utilization of nutrients after a meal than the T2 or T6 gilts.The T1 gilts also had a higher acetate content and SCFAs in feces than the T6 gilts(P<0.05).The age,body weight and backfat thickness of the gilts at first estrous expression were not affected by the meal frequency,but the gilts in the T1 group had higher levels of serum luteinizing hormone on the 18th day of t

关 键 词：GILTS Luteinizing hormone Meal frequency Nutrient utilization Ovarian follicular development 

分 类 号：S828[农业科学—畜牧学]