老年患者无痛胃镜检查中麻醉药物的应用及效果研究  

Application and Effect of Anesthetics in Painless Gastroscopy in Elderly Patients

作　　者：李勇 赵同新[1] LI Yong;ZHAO Tongxin(Department of Anesthesiology,Shanxian Central Hospital,Shanxian,Shandong Province,274399 China)

机构地区：[1]单县中心医院麻醉科,山东单县274399

出　　处：《系统医学》2021年第11期33-35,73,共4页Systems Medicine

摘　　要：目的分析老年患者无痛胃镜检查中麻醉药物的应用及效果。方法选取2019年1月—2020年1月该院收治的老年无痛胃镜检查患者180例作为研究对象,根据1∶1的配比方式分为两组,每组90例,观察组行舒芬太尼镇痛、丙泊酚联合依托咪酯镇静,对照组行舒芬太尼镇痛、单一丙泊酚镇静,对比两组患者两组患者检查指标、临床指标、术后MMSE评分及不良反应发生率。结果观察组心率(77.35±6.46)次/min;收缩压(119.34±6.26)mmHg,舒张压(89.35±6.21)mmHg均优于对照组,差异有统计学意义(t=5.744、5.525、3.805,P<0.001)。观察组不良反应(1.11%)低于对照组,差异有统计学意义(χ^(2)=4.211,P=0.040)。观察组检查时间(3.53±0.12)min,麻醉唤醒时间(4.52±0.23)min,下床时间(19.63±2.97)min均低于对照组,差异有统计学意义(t=4.303、5.306、4.538,P<0.001)。观察组术后1 d、2 d、3 d MMSE评分为(27.41±1.25)分、(23.45±2.48)分、(26.89±1.25)分,均高于对照组,差异有统计学意义(t=7.864、7.652、14.275,P<0.001)。结论舒芬太尼镇痛、丙泊酚联合依托咪酯镇静在老年无痛胃镜检查患者的麻醉中有着良好的应用效果,能够有效缩短患者的麻醉唤醒时间,降低不良反应发生率,值得广泛的应用与推广。Objective To analyze the application and effect of anesthetics in painless gastroscopy in elderly patients.Methods A total of 180 elderly patients undergoing painless gastroscopy admitted to the hospital from January 2019 to January 2020 were selected as the research objects.They were divided into two groups according to a 1∶1 ratio,with 90 cases in each group.The observation group was treated with Sufen Tanyl analgesia,propofol combined with etomidate sedation,the control group received sufentanil analgesia,single propofol sedation,the two groups of patients were compared with the two groups of patients,clinical indicators,postoperative MMSE scores and adverse reactions incidence rate.Results The heart rate of the observation group was(77.35±6.46)beats/min,systolic blood pressure(119.34±6.26)mmHg,diastolic blood pressure(89.35±6.21)mmHg,better than the control group,the difference was statistically significant(t=5.744、5.525、3.805,P<0.001).The adverse reaction of the observation group was 1.11%lower than that of the control group,the difference was statistically significant(χ^(2)=4.211,P=0.040).The examination time of the observation group was(3.53±0.12)min,the awakening time of anesthesia was(4.52±0.23)min,the time to get out of bed was(19.63±2.97)min,lower than the control group,the difference was statistically significant(t=4.303、5.306、4.538,P<0.001).The MMSE scores of the observation group were(27.41±1.25)points,(23.45±2.48)points,and(26.89±1.25)points at 1 d,2 d,and 3 d after operation.The results were higher than the control group,the difference was statistically significant(t=7.864、7.652、14.275,P<0.001).Conclusion Sufentanil analgesia,propofol combined with etomidate sedation have a good application effect in the anesthesia of elderly patients undergoing painless gastroscopy.They can effectively shorten the patient's anesthesia wake-up time and reduce the incidence of adverse reactions.It is worthy of extensive use Application and promotion.

关 键 词：无痛胃镜 麻醉药物 丙泊酚 依托咪酯 麻醉效果 

分 类 号：R614[医药卫生—麻醉学]