持续小剂量舒芬太尼输注对老年高血压手术患者麻醉恢复期血流动力学指标的影响  

The Effect of Continuous Low-dose Sufentanil Infusion on Hemodynamic Indexes during Recovery from Anesthesia in Elderly Hypertensive Patients

作　　者：吴琼 WU Qiong(Department of Anesthesiology,Beijing Renhe Hospital,Beijing,102600 China)

机构地区：[1]北京仁和医院麻醉科,北京102600

出　　处：《系统医学》2021年第11期77-79,共3页Systems Medicine

摘　　要：目的探讨持续小剂量舒芬太尼输注对老年高血压手术患者麻醉恢复期血流动力学指标的影响。方法选择2018年4月—2020年3月该院收治的老年高血压手术患者106例,以随机数表法分为对照组与研究组,各53例。研究组持续应用小剂量0.1μg/(kg·h)舒芬太尼,初始剂量0.25 mg/(kg·min)瑞芬太尼与1%~2%七氟烷吸入麻醉维持;对照组应用0.25 mg/(kg·min)瑞芬太尼与1%~2%七氟烷吸入麻醉维持。对比两组入手术室时、拔管即刻与拔管后15 min的心率、平均动脉压;拔管时间;拔管后的Ramsay镇静评分。结果研究组拔管即刻、拔管后15 min时心率(86.68±4.80)、(75.67±3.53)次/min,平均动脉压(87.68±5.64)、(85.63±6.02)mmHg,均低于对照组(95.66±5.31)次/min、(82.64±4.30)次/min、(95.76±7.52)mmHg、(91.55±6.00)mmHg,差异有统计学意义(t=9.133、9.121、6.258、5.071,P<0.05)。研究组拔管时间(11.50±2.63)min与对照组(12.00±2.85)min对比差异无统计学意义(t=0.939,P>0.05)。研究组拔管后镇静评分(1.98±0.20)分高于对照组(1.68±0.23)分,差异有统计学意义(t=7.166,P<0.05)。结论持续小剂量舒芬太尼输注可以有效稳定老年高血压手术患者麻醉恢复期血流动力学指标。Objective To investigate the effect of continuous low-dose sufentanil infusion on hemodynamic parameters during recovery from anesthesia in elderly hypertensive patients.Methods A total of 106 elderly hypertensive surgery patients admitted to the hospital from April 2018 to March 2020 were selected and divided into the control group and the study group with 53 cases each by random number table.The study group continued to use a small dose of 0.1μg/(kg·h)sufentanil,an initial dose of 0.25 mg/(kg·min)remifentanil and 1%~2%sevoflurane for maintenance of inhalation anesthesia;the control group received 0.25 mg/(kg·min)remifentanil and 1%~2%sevoflurane inhalation anesthesia was maintained.The heart rate and mean arterial pressure when the two groups entered the operating room,immediately after extubation and 15 minutes after extubation;extubation time;Ramsay sedation score after extubation.Results Immediately after extubation,the heart rate of the study group was(86.68±4.80)beats/min,(75.67±3.53)beats/min,mean arterial pressure(87.68±5.64)mmHg,(85.63±6.02)mmHg,both lower than the control group(95.66±5.31)times/min,(82.64±4.30)times/min,(95.76±7.52)mmHg,(91.55±6.00)mmHg,the difference was statistically significant(t=9.133,9.121,6.258,5.071,P<0.05).There was no statistically significant difference in the extubation time between the study group(11.50±2.63)min and the control group(12.00±2.85)min(t=0.939,P>0.05).The score of sedation after extubation in the study group(1.98±0.20)points was higher than that of the control group(1.68±0.23)points,the difference was statistically significant(t=7.166,P<0.05).Conclusion Continuous low-dose sufentanil infusion can effectively stabilize the hemodynamic parameters of elderly hypertensive patients during anesthesia recovery.

关 键 词：舒芬太尼 老年 高血压 手术 麻醉恢复期 血流动力学 

分 类 号：R614[医药卫生—麻醉学]