腰大池引流联合阿托伐他汀治疗进展型创伤性硬膜下积液的临床疗效观察  

Clinical observation of lumbar cistern drainage combined with Atorvastatin in the treatment of progressive traumatic subdural effusion

作　　者：黄永生[1] 朱丽琴[1] 宋志英[1] 王佑招 Huang Yongsheng;Zhu Liqin;Song Zhiying(The People's Hospital of Huichang County,Huichang,Jiangxi 342600)

机构地区：[1]会昌县人民医院,江西会昌342600

出　　处：《基层医学论坛》2021年第26期3737-3738,共2页The Medical Forum

基　　金：赣州市指导性科技计划课题(GZ2020ZSF725)。

摘　　要：目的探讨进展型创伤性硬膜下积液患者采用腰大池引流联合阿托伐他汀治疗的临床疗效。方法选取2020年1月—9月在会昌县人民医院治疗的进展型创伤性硬膜下积液患者60例作为研究对象,按照治疗方法的不同分成观察组和对照组各30例。对照组采用钻孔引流术治疗,观察组采用腰大池穿刺持续引流术联合阿托伐他汀钙片口服治疗,比较2组患者硬膜下积液量、积液厚度、颅内压情况,随访6个月,统计临床结局。结果观察组颅内压恢复正常时间明显短于对照组(P<0.05),硬膜下积液量明显少于对照组(P<0.05),积液厚度明显低于对照组(P<0.05);随访6个月,观察组格拉斯哥预后(GOS)评分明显高于对照组(P<0.05)。结论进展型创伤性硬膜下积液患者采用腰大池引流联合阿托伐他汀治疗效果显著,可减少积液量,改善预后,值得临床推广。Objective To investigate the clinical efficacy of lumbar cistern drainage combined with atorvastatin in patients with progressive traumatic subdural effusion.Methods Sixty patients with progressive traumatic subdural effusion who were treated in Huichang County People’s Hospital from January 2020 to September 2020 were selected as the research objects.According to the different treatment methods,they were divided into observation group and control group with 30 cases each.The control group was treated with drilling and drainage,and the observation group was treated with lumbar cistern puncture and continuous drainage combined with atorvastatin calcium tablets orally.The two groups of patients were compared in terms of subdural effusion volume,effusion thickness,intracranial pressure,Follow-up for 6 months,statistical clinical outcome.Results The time to return to normal intracranial pressure in the observation group was significantly shorter than that in the control group(P<0.05),the amount of subdural effusion was significantly less than that in the control group(P<0.05),and the thickness of the effusion was significantly lower than that in the control group(P<0.05);after 6 months of follow-up,the Glasgow Outcome(GOS)score of the observation group was significantly higher than that of the control group(P<0.05).Conclusion In patients with progressive traumatic subdural effusion,the treatment of lumbar cistern drainage combined with atorvastatin has a significant effect,which can reduce the amount of effusion.It is worthy of clinical promotion.

关 键 词：硬膜下积液 进展型创伤性 腰大池引流 阿托伐他汀 临床疗效 

分 类 号：R4[医药卫生—临床医学]