Pediatric case with vaccine-related poliovirus infection: A case report  

作　　者：Reza Taherkhani Fatemeh Farshadpour 

机构地区：[1]Department of Virology,School of Medicine,Bushehr University of Medical Sciences,Bushehr 7514633341,Iran

出　　处：《World Journal of Clinical Pediatrics》2021年第5期106-111,共6页世界临床儿科杂志

基　　金：Supported by Deputy Research and Affairs of Bushehr University of Medical Sciences,Bushehr,Iran,No.4359.

摘　　要：BACKGROUND As long as oral poliovirus vaccine(OPV)is used,the potential risk for the emergence of vaccine-related polioviruses remains.CASE SUMMARY We report a case of Sabin-like type 1 poliovirus infection in an immunocompetent 17-mo-old child after receiving four scheduled doses of OPV.Somehow,the four doses did not confer full protection,possibly because of interference created by other enteroviruses.CONCLUSION The surveillance of vaccine-related polioviruses has important implications for improving health policies and vaccination strategies.Missed cases of vaccinerelated poliovirus infection might pose a potential risk to global poliovirus eradication.Therefore,the global withdrawal of OPV and a shift to the inclusion of only inactivated poliovirus vaccine in the vaccination schedule is the main objective of the polio eradication program.

关 键 词：POLIOVIRUS Oral poliovirus vaccine Vaccine-associated paralytic poliomyelitis Case report 

分 类 号：R725.1[医药卫生—儿科]