Severe Anemia in a Patient With Mild T Cell Hypofunction Infected With Parvovirus B19  

作　　者：Xiaoxin Wu Xiumei Zhou Liang Yu Junchen Linjian Zhang Jiaqi Li Yalei Zhao Xiaowei Xu 

机构地区：[1]State Key Laboratory for Diagnosis and Treatment of Infectious Diseases,National Clinical Research Center for Infectious Diseases,Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases,The First Affiliated Hospital,College of Medicine,Zhejiang University,Hangzhou 310003,China [2]Department of Infectious Diseases,People’s Hospital of Pujiang County,Zhejiang Province,Pujiang Branch of the First Affiliated Hospital,College of Medicine,Zhejiang University,China

出　　处：《Infectious Microbes & Diseases》2020年第2期83-85,共3页感染微生物与疾病（英文）

基　　金：Funding for this work was provided by the Science and Technology Key Program of Zhejiang province,China(Grant No.2017C03051);Zhejiang Province Medical and Health Science and Technology Program(Grant No.2020379356 and 2020377610).

摘　　要：Background Parvovirus B19 is a single-stranded DNA virus with a 5.6 kilobase DNA genome and a diameter of 22–24nm.1 This virus does not possess an envelope and it is the most pathogenic virus belonging to the family of Parvoviridae that infects human beings.2 The main diseases caused by parvovirus B19 are as follows:(1)infectious erythema(also known as fifth disease,erythema infection),a cause of a common rash in pediatric patients;(2)joint disease;(3)aplastic anemia crisis in patients with chronic hemolytic disease;(4)chronic anemia in immunodeficient patients;(5)fetal hydrops in addition to stillbirth and abortion(fetal death).

关 键 词：severe anemia parvovirus B19 next generation sequencing 

分 类 号：R556[医药卫生—血液循环系统疾病]